MMPIP (hydrochloride) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

MMPIP is a reversible allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) that blocks agonist-induced calcium mobilization (IC₅₀ = 26 nM). It does not affect other mGlu receptors. The modulation of mGluR7 by MMPIP is context dependent, in that it is not observed in all known mGluR7 signaling pathways. MMPIP has been used to investigate the role of mGluR7 in cocaine-mediated reward signaling, attention and impulse control, and cognitive behavior in mice and rats. MMPIP also reversibly inhibits constitutive activity of mGluR7 in sympathetic neurons from the rat superior cervical ganglion.

Verwenden

MMPIP Hydrochloride is a reversible allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) that blocks agonist-induced calcium mobilization.

MMPIP (hydrochloride) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

MMPIP (hydrochloride) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32965	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Shanghai Chaolan Chemical Technology Center	021-QQ：65489617 15618227136	Sales@ATKchemical.com	China	7312	58
Shanghai SuperLan Chemcial Technique Centre	021-2022843681 15618226720	lucy@atkchemical.com	China	9987	58
Medi-tech Bioscientific Co., Ltd.	0519-83246372 13585352506		China	1844	58
Cckinase, Inc.	+1 (732)236-3202	sales@cckinase.com	United States	2738	58
Absin Bioscience Inc.	021-38015121 15000105423	wulan@absin.cn	China	24731	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44807	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24644	58

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• 6-chloro-5-methyl-N-[6-(2-methylpyridin-3-yl)oxypyridin-3-yl]-2,3-dihydroindole-1-carboxamide
• 242084
• CS-1472
• CS-2104
• SB-242084 HCl
• MMPIP hydrochloride (479077-02-6 Free base)
• MMPIP hydrochloride,MMPIP,system,nervous,neuropathic,behavior,pain,inhibit,central,glutamate,cognitive,allosteric,Metabotropic glutamate receptors,Inhibitor,metabotropic,mGluR,mGluR7
• MMPIP hydrochloride, 10 mM in DMSO
• 1215566-78-1