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Desoxycorton

Desoxycorticosterone Struktur
64-85-7
CAS-Nr.
64-85-7
Bezeichnung:
Desoxycorton
Englisch Name:
Desoxycorticosterone
Synonyma:
DOC;CORTEXONE;Corthormon;Deoxycortone;Desoxycorton;DOC【steroid】;DESOXYCORTONE;'REICHSTEIN Q';DEOXYCORTICOSTERONE;DESOXYCORTICOSTERONE
CBNumber:
CB4314147
Summenformel:
C21H30O3
Molgewicht:
330.46
MOL-Datei:
64-85-7.mol

Desoxycorton Eigenschaften

Schmelzpunkt:
138-144 °C
alpha 
184 º (c=1, C2H5OH)
Siedepunkt:
407.89°C (rough estimate)
Dichte
1.0998 (rough estimate)
Brechungsindex
1.5192 (estimate)
Flammpunkt:
9℃
storage temp. 
-20°C
L?slichkeit
Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
12.98±0.10(Predicted)
Farbe
White to Pale Yellow
Optische Aktivit?t
+17822 (c 1.5, ethanol)
Wasserl?slichkeit
slightly soluble
Merck 
13,2917
BRN 
2062123
LogP
2.880
CAS Datenbank
64-85-7(CAS DataBase Reference)
NIST chemische Informationen
Deoxycorticosterone(64-85-7)
EPA chemische Informationen
Deoxycorticosterone (64-85-7)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,T,F
R-S?tze: 40-48-39/23/24/25-23/24/25-11
S-S?tze: 22-24/25-45-36/37-16-7
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
RTECS-Nr. HG0350000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H351 Kann vermutlich Krebs verursachen. Karzinogenit?t Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
H373 Kann die Organe sch?digen bei l?ngerer oder wiederholter Exposition. Spezifische Zielorgan-Toxizit?t (wiederholte Exposition) Kategorie 2 Warnung P260, P314, P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.

Desoxycorton Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R40:Verdacht auf krebserzeugende Wirkung.
R48:Gefahr ernster Gesundheitssch?den bei l?ngerer Exposition.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

white to creamy-white crystalline powder

Verwenden

A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).

Definition

ChEBI: A mineralocorticoid that is progesterone substituted at position 21 by a hydroxy group.

Allgemeine Beschreibung

11-Deoxycorticosterone is a steroid hormone produced in the adrenal glands that acts as a precursor for the hormone aldosterone. Levels of 11-deoxycorticosterone are measured by LC-MS/MS to aid in diagnosing disorders of steroid synthesis, such as 11-hydroxylase deficiency and glucocorticoid responsive hyperaldosteronism. This Certified Spiking Solution? is suitable for use as starting material inlinearity standards, calibrators, and controls for numerous LC-MS/MS applications in endocrinology, clinical chemistry, and neonatal screening.

Hazard

Toxic.

Mechanism of action

Desoxycorticosterone causes an increase in reabsorption of sodium ions and excretion of potassium ions from the renal tubules, which leads to increased tissue hydrophilicity. This facilitates an elevated volume of plasma and increased arterial pressure. Muscle tonicity and work capability are increased. It is used for an insufficiency of function of the adrenal cortex, myasthenia, asthenia, adynamia, and overall muscle weakness.

l?uterung methode

Crystallise 11-deoxycorticosterone from diethyl ether. [Schindler et al. Helv Chim Acta 24 360 1941, Steiger & Reichstein Helv Chim Acta 20 1164 1937.]

Desoxycorton Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Desoxycorton Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 142)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Hubei xin bonus chemical co. LTD
86-13657291602
linda@hubeijusheng.com CHINA 22963 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32002 58
Wuhan Fortuna Chemical Co., Ltd
+86-027-59207850
info@fortunachem.com China 5986 58
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923
1026@dideu.com China 8670 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522
overseasales@yongstandards.com China 11922 58
Wuhan Quanjinci New Material Co.,Ltd.
+86-15271838296; +8615271838296
kyra@quanjinci.com China 1512 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501
product@acmec-e.com China 33338 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
cooperation@kean-chem.com China 40066 58

64-85-7(Desoxycorton)Verwandte Suche:


  • Corthormon
  • Corticosterone, 11-deoxy-
  • Deoxycortone
  • Pregn-4-en-21-ol-3,20-dione
  • Pregn-4-ene-3,20-dione, 21-hydroxy-
  • Progesterone, 21-hydroxy-
  • deoxycorticosterone crystalline
  • Desoxycorton
  • 21-HYDROXYPROGESTERON VETRANAL, 250 MG
  • 17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  • HYDROXYPROGESTERONE, 21-(RG)
  • Reichstein Q, 11-Deoxycorticosterone, 11-Desoxycorticosterone, 21-Hydroxy-4-pregnene-3,20-dione, 4-Pregnen-21-ol-3,20-dione, Cortexone, Desoxycortone, DOC, Kendalls desoxy compound B
  • Deoxycorticosterone Propionate
  • DOC【steroid】
  • DesoxycorticosteroneDeoxycorticosterone
  • 21-Hydroxy-3,20-dioxopregn -4-ene
  • 21-Hydroxy-4-pregnane-3,20-dione
  • CORTEXONE
  • DELTA4-PREGNEN-21-OL-3,20-DIONE
  • DEOXYCORTICOSTERONE
  • DESOXYCORTICOSTERONE
  • DESOXYCORTONE
  • DOC
  • HYDROXYPROGESTERONE, 21-
  • KENDALL'S DESOXY COMPOUND B
  • 4-PREGNENE-21-OL-3,20-DIONE
  • 4-PREGNEN-21-OL-3,20-DIONE
  • 11-DESOXYCORTICOSTERONE
  • 11-DEOXYCORTICOSTERONE
  • 21-HYDROXY-4-PREGNENE-3,20-DIONE
  • 21-hydroxypregn-4-ene-3,20-dione
  • 21-HYDROXYPROGESTERONE
  • 'REICHSTEIN Q'
  • REICHSTEIN'S COMPOUND ''Q''
  • REICHSTEIN'S SUBSTANCE Q
  • (8S,10R,13S,17S)-17-(2-Hydroxy-acetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
  • 11-Dehydroxycorticosterone
  • 21-Hydroxypregn-4-en-3,20-dione
  • 21-hydroxy-progesteron
  • Desoxycorticosterone Solution, 100ppm
  • 11-Deoxycorticosterone solution
  • Corticosterone Impurity 5
  • 11-Deoxycorticosterone-2,3,4-13C3 solution 100 mug/mL in methanol, >=99 atom % 13C, >=98% (CP)
  • Desoxycorticosterone USP/EP/BP
  • 21-hydroxyprogesteroneQ: What is 21-hydroxyprogesterone Q: What is the CAS Number of 21-hydroxyprogesterone Q: What is the storage condition of 21-hydroxyprogesterone
  • 13C2,2H2]-Deoxycorticosterone
  • 2H6]-Deoxycorticosterone
  • 2H4]-11-Deoxycorticosterone
  • 64-85-7
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
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