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BAFILOMYCIN B1

BAFILOMYCIN B1 Struktur
88899-56-3
CAS-Nr.
88899-56-3
Englisch Name:
BAFILOMYCIN B1
Synonyma:
CID 74030053;BAFILOMYCIN B1;BAFILOMYCIN B1 USP/EP/BP;ino)carbonyl)-2-methoxy-24-methyl-;bafilomycin b1from streptomyces sp.;BafilomycinB1fromStreptomycesgriseus;BAFILOMYCIN B1 MONOHYDRATE FROM STREPTO- MYCES SPECIES;hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am;37-De(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin;2-Butenoic acid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-, (2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethy...
CBNumber:
CB4312754
Summenformel:
C44H65NO13
Molgewicht:
815.99
MOL-Datei:
88899-56-3.mol

BAFILOMYCIN B1 Eigenschaften

storage temp. 
−20°C
L?slichkeit
DMSO: Soluble; Methanol: Unstable
Aggregatzustand
powder or crystals
Farbe
faint yellow to yellow
BRN 
4640118
Stabilit?t:
Hygroscopic

Sicherheit

Kennzeichnung gef?hrlicher T+
R-S?tze: 26/27/28
S-S?tze: 36/37/39-45
RIDADR  UN 3462 6.1/PG 1
WGK Germany  3
RTECS-Nr. NG8841000
10-21
HazardClass  3
HS Code  2941900000

BAFILOMYCIN B1 Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Beschreibung

Bafilomycin B1 is a fungal metabolite that has been found in Streptomyces and has diverse biological activities. It inhibits the activity of rat liver lysosomal vacuolar H+-ATPase (V-ATPase) in a concentration-dependent manner. Bafilomycin B1 (10-1,000 nM) induces autophagosome accumulation in MCF-7 cells. It inhibits chloroquine-induced apoptosis in primary cerebellar granule neurons (CGNs) when used at a concentration of 1 nM. Bafilomycin B1 reduces viral genome copy numbers in the culture supernatant of Vero E6 cells infected with H1N1 influenza A.

Verwenden

Bafilomycin B1 is a member of a potent family of macrocyclic lactones. Bafilomycin B1 shares the same mode of action and activity as its more accessible A1 analogue. Bafilomycin B1 is broadly active against bacteria, fungi, insects, nematodes and protozoans. Bafilomycin B1 has attracted interest as a potential agent for treating osteoporosis.

BAFILOMYCIN B1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


BAFILOMYCIN B1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 66)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32080 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22883 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19741 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38470 58
Guangzhou CATO Research Chemicals Inc.
+86-020-81960175-617 +8615602392859
Intermediate@cato-chem.com China 8056 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969
isunpharm@qq.com China 4428 55
Codow Chemical Co.,Ltd. 18620099427
amy@howeipharm.com China 17687 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
Shanghai Xilong Biochemical Technology Co., Ltd. 021-52907766-8042
China 9941 58

88899-56-3()Verwandte Suche:


  • BAFILOMYCIN B1
  • BAFILOMYCIN B1 MONOHYDRATE FROM STREPTO- MYCES SPECIES
  • BafilomycinB1fromStreptomycesgriseus
  • bafilomycin b1from streptomyces sp.
  • hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am
  • ino)carbonyl)-2-methoxy-24-methyl-
  • 37-De(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin
  • 2-Butenoic acid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-, (2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethy...
  • BAFILOMYCIN B1 USP/EP/BP
  • CID 74030053
  • 88899-56-3
  • C44H65NO13
  • Antibiotics
  • Antibiotics A-F
  • Antibiotics A to Z
  • BioChemical
  • Antibiotic
  • MacrolidesMore...Close...
  • A - KAntibiotics
  • Antibacterial
  • Antibiotics A to
  • Antibiotics A-FAntibiotics
  • Antibiotics by Application
  • AntifungalAntibiotics
  • Antineoplastic and Immunosuppressive AntibioticsAntibiotics
  • Chemical Structure Class
  • Inhibits an EnzymeAntibiotics
  • Mechanism of Action
  • Spectrum of Activity
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