BAFILOMYCIN B1
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BAFILOMYCIN B1 Eigenschaften
- storage temp.
- −20°C
- L?slichkeit
- DMSO: Soluble; Methanol: Unstable
- Aggregatzustand
- powder or crystals
- Farbe
- faint yellow to yellow
- BRN
- 4640118
- Stabilit?t:
- Hygroscopic
Sicherheit
Kennzeichnung gef?hrlicher | T+ | ||
---|---|---|---|
R-S?tze: | 26/27/28 | ||
S-S?tze: | 36/37/39-45 | ||
RIDADR | UN 3462 6.1/PG 1 | ||
WGK Germany | 3 | ||
RTECS-Nr. | NG8841000 | ||
F | 10-21 | ||
HazardClass | 3 | ||
HS Code | 2941900000 |
BAFILOMYCIN B1 Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.S-S?tze Betriebsanweisung:
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Beschreibung
Bafilomycin B1 is a fungal metabolite that has been found in Streptomyces and has diverse biological activities. It inhibits the activity of rat liver lysosomal vacuolar H+-ATPase (V-ATPase) in a concentration-dependent manner. Bafilomycin B1 (10-1,000 nM) induces autophagosome accumulation in MCF-7 cells. It inhibits chloroquine-induced apoptosis in primary cerebellar granule neurons (CGNs) when used at a concentration of 1 nM. Bafilomycin B1 reduces viral genome copy numbers in the culture supernatant of Vero E6 cells infected with H1N1 influenza A.Verwenden
Bafilomycin B1 is a member of a potent family of macrocyclic lactones. Bafilomycin B1 shares the same mode of action and activity as its more accessible A1 analogue. Bafilomycin B1 is broadly active against bacteria, fungi, insects, nematodes and protozoans. Bafilomycin B1 has attracted interest as a potential agent for treating osteoporosis.BAFILOMYCIN B1 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
BAFILOMYCIN B1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 66)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 22787 | 58 |
BOC Sciences | 16314854226; +16314854226 |
inquiry@bocsci.com | United States | 19741 | 58 |
TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38631 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 94657 | 76 |
Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 |
isunpharm@qq.com | China | 4674 | 55 |
Codow Chemical Co.,Ltd. | 18620099427 |
amy@howeipharm.com | China | 17687 | 55 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9806 | 58 |
Shanghai Xilong Biochemical Technology Co., Ltd. | 021-52907766-8042 |
China | 9941 | 58 | |
Lynnchem | 86-(0)29-85992781 17792393971 |
info@lynnchem.com | China | 4587 | 58 |
88899-56-3()Verwandte Suche:
- BAFILOMYCIN B1
- BAFILOMYCIN B1 MONOHYDRATE FROM STREPTO- MYCES SPECIES
- BafilomycinB1fromStreptomycesgriseus
- bafilomycin b1from streptomyces sp.
- hygrolidin,37-decarboxy-2-demethyl-37-(((2-hydroxy-5-oxo-1-cyclopenten-1-yl)am
- ino)carbonyl)-2-methoxy-24-methyl-
- 37-De(carboxy)-2-demethyl-37-[[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]carbonyl]-2-methoxy-24-methylhygrolidin
- 2-Butenoic acid, 4-[(2-hydroxy-5-oxo-1-cyclopenten-1-yl)amino]-4-oxo-, (2R,4R,5S,6R)-tetrahydro-2-hydroxy-2-[(1S,2R,3S)-2-hydroxy-3-[(2R,3S,4E,6E,9S,10S,11R,12E,14Z)-10-hydroxy-3,15-dimethoxy-7,9,11,13-tetramethyl-16-oxooxacyclohexadeca-4,6,12,14-tetraen-2-yl]-1-methylbutyl]-5-methyl-6-(1-methylethy...
- BAFILOMYCIN B1 USP/EP/BP
- CID 74030053
- 88899-56-3
- C44H65NO13
- Antibiotics
- Antibiotics A-F
- Antibiotics A to Z
- BioChemical
- Antibiotic
- MacrolidesMore...Close...
- A - KAntibiotics
- Antibacterial
- Antibiotics A to
- Antibiotics A-FAntibiotics
- Antibiotics by Application
- AntifungalAntibiotics
- Antineoplastic and Immunosuppressive AntibioticsAntibiotics
- Chemical Structure Class
- Inhibits an EnzymeAntibiotics
- Mechanism of Action
- Spectrum of Activity