IFN-2, B cell differentiation factor (BCDF) Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
IL-6 from mouse has been used to study IL-6-mediated inhibition of mouse preadipocyte differentiation.
Allgemeine Beschreibung
Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant murine IL-6 is a 21.7 kDa protein containing 188 amino acid residues.
Biochem/physiol Actions
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R and gp130.
IFN-2, B cell differentiation factor (BCDF) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
