N-(2-Aminophenyl)pyrazine-2-carboxamide
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- CAS-Nr.
- 926259-99-6
- Englisch Name:
- N-(2-Aminophenyl)pyrazine-2-carboxamide
- Synonyma:
- BG45;CS-2040;BG45;BG 45;45, HDAC3 Inhibitor;BG45, 10 mM in DMSO;BG45, HDAC3 Inhibitor;B 45, HDAC3 Inhibitor;N-(2-Aminophenyl)pyrazine-2-carboxamide;n-(2-aminophenyl)-2-pyrazinecarboxamide;2-Pyrazinecarboxamide, N-(2-aminophenyl)-
- CBNumber:
- CB42750697
- Summenformel:
- C11H10N4O
- Molgewicht:
- 214.22
- MOL-Datei:
- 926259-99-6.mol
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N-(2-Aminophenyl)pyrazine-2-carboxamide Eigenschaften
- Schmelzpunkt:
- 160-163°C
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: soluble20mg/mL, clear
- Aggregatzustand
- powder
- Farbe
- white to beige
N-(2-Aminophenyl)pyrazine-2-carboxamide Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
BG45 is an HDAC class I inhibitor with selectivity for HDAC3 (IC
50 = 289 nM). It inhibits HDAC1, HDAC2, and HDAC6 with greatly reduced potency (IC
50s = 2, 2.2, and >20 μM, respectively). At concentrations up to 50 mg/kg, BG45 alone or in combination with bortezomib has been shown to dose-dependently inhibit tumor growth in a mouse model of multiple myeloma.
N-(2-Aminophenyl)pyrazine-2-carboxamide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
N-(2-Aminophenyl)pyrazine-2-carboxamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 75)Lieferanten
- BG45
- N-(2-Aminophenyl)pyrazine-2-carboxamide
- PYRAZINE-2-CARBOXYLIC ACID-(2-AMINO-ANILIDE)
- BG45, 98%, a HDAC class I inhibitor with selectivity for HDAC3
- BG45, HDAC3 Inhibitor
- BG45;BG 45
- CS-2040
- 45, HDAC3 Inhibitor
- 2-Pyrazinecarboxamide, N-(2-aminophenyl)-
- Inhibitor,inhibit,BG45,HDAC,Histone deacetylases,BG-45,BG 45,Apoptosis
- n-(2-aminophenyl)-2-pyrazinecarboxamide
- B 45, HDAC3 Inhibitor
- BG45, 10 mM in DMSO
- 926259-99-6
- Inhibitors
