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  • (S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one

    (S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one Struktur
    1523404-29-6
    CAS-Nr.
    1523404-29-6
    Englisch Name:
    (S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one
    Synonyma:
    129208;Vps34-IN-2;Vps34 inhibitor 2;Vps-34-IN-2,Vps34 IN 2,Vps34IN2;(S)-1-(3-Methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyri;(S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one;(S)-9-(3-Methyl-2-oxobutyl)-2-((R)-3-methylmorpholino)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one;(8S)-6,7,8,9-Tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one;4H-Pyrimido[1,2-a]pyrimidin-4-one, 6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-, (8S)-
    CBNumber:
    CB42742380
    Summenformel:
    C18H25F3N4O3
    Molgewicht:
    402.41
    MOL-Datei:
    1523404-29-6.mol

    (S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one Eigenschaften

    Siedepunkt:
    466.4±55.0 °C(Predicted)
    Dichte
    1.40±0.1 g/cm3(Predicted)
    storage temp. 
    Sealed in dry,Room Temperature
    L?slichkeit
    Ethanol: 50 mg/mL (124.25 mM)
    pka
    0.08±0.40(Predicted)
    Aggregatzustand
    Solid
    Farbe
    White to off-white

    Sicherheit

    (S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one Chemische Eigenschaften,Einsatz,Produktion Methoden

    Verwenden

    (8S)-6,7,8,9-Tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one, is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively.

    (S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one Upstream-Materialien And Downstream Produkte

    Upstream-Materialien

    Downstream Produkte


    (S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

    Global( 15)Lieferanten
    Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
    TargetMol Chemicals Inc.
    +1-781-999-5354 +1-00000000000
    marketing@targetmol.com United States 32161 58
    TargetMol Chemicals Inc.

    support@targetmol.com United States 38631 58
    TargetMol Chemicals Inc.
    +8613564774135
    zijue.cai@tsbiochem.com United States 19884 58
    ChemShuttle, Inc. 0510-83588313-802 18800520310;
    sales@chemshuttle.com China 3002 62
    Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057
    3003855609@qq.com China 7787 56
    Taizhou Crene Biotechnology Co. Ltd. +86-0576-88813233 +86-13396860566
    sales@pharm-intermediates.com China 1991 58
    ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
    sales@chemegen.com China 11218 58
    Shanghai hongqu biomedical technology co. LTD 88888888888
    hongquchem@qq.com China 5132 58
    Changzhou Furuisi Biotechnology Co., Ltd 0519-85524369
    3477467573@qq.com China 8617 58
    Bide Pharmatech Ltd. 400-1647117 13681763483
    product02@bidepharm.com China 62075 58

    • (S)-1-(3-methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one
    • (S)-1-(3-Methyl-2-oxobutyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyri
    • (8S)-6,7,8,9-Tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one
    • 4H-Pyrimido[1,2-a]pyrimidin-4-one, 6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-, (8S)-
    • Vps34 inhibitor 2
    • 129208
    • Vps34-IN-2
    • Vps-34-IN-2,Vps34 IN 2,Vps34IN2
    • (S)-9-(3-Methyl-2-oxobutyl)-2-((R)-3-methylmorpholino)-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one
    • 1523404-29-6
    • C18H25F3N4O3
    • API
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