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Oligomycin A

OLIGOMYCIN A Struktur
579-13-5
CAS-Nr.
579-13-5
Bezeichnung:
Oligomycin A
Englisch Name:
OLIGOMYCIN A
Synonyma:
OLIGOMYCIN COMPLEX;CS-1898;Oli;MCH 32;mycin A;AOligoMyci;OLIGOMYCIN A;Oligomycin A, >=98%;Oligomycin A MCH 32;OLIGOMYCIN A USP/EP/BP
CBNumber:
CB4274065
Summenformel:
C45H74O11
Molgewicht:
791.06
MOL-Datei:
579-13-5.mol

Oligomycin A Eigenschaften

Schmelzpunkt:
150-151℃
Siedepunkt:
886.3±65.0 °C(Predicted)
Dichte
1.14
storage temp. 
Sealed in dry,Store in freezer, under -20°C
L?slichkeit
Soluble in DMSO, ethanol or acetone
pka
12.52±0.70(Predicted)
Aggregatzustand
powder
Farbe
white to off-white
Merck 
13,6902
BRN 
5702132
InChIKey
MNULEGDCPYONBU-WMBHJXFZSA-N
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn,T
R-S?tze: 22-68/20/21/22-20/21/22
S-S?tze: 36/37-24/25
RIDADR  2811
WGK Germany  3
RTECS-Nr. RK3325000
3-10
HazardClass  6.1(b)
PackingGroup  III
HS Code  29419090
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P330 Mund ausspülen.

Oligomycin A Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.
R68/20/21/22:Gesundheitssch?dlich: M?glichkeit irreversiblen Schadens durch Einatmen,Berührung mit der Haut und durch Verschlucken.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.

Beschreibung

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin A, a dominant analog of the isomers, is an inhibitor of mitochondrial F1FO ATP synthase that induces apoptosis in a variety of cell types (average GI50 = 270 nM). Oligomycin A exhibits antifungal, antitumor, and nematocidal activities, but has poor solubility in water and other biocompatible solvents, which limits its clinical application.

Chemische Eigenschaften

White powder

Verwenden

Oligomycin A is a macrolide with fungicidal activity isolated from Streptomyces species.

Oligomycin A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Oligomycin A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 178)Lieferanten
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579-13-5(Oligomycin A)Verwandte Suche:


  • OLIGOMYCIN A, STREPTOMYCES DIASTATOCHROMOGENES
  • OLIGOMYCIN A
  • OLIGOMYCIN, STREPTOMYCES DIASTATOCHROMOGENES
  • Oligomycin A fromStreptomyces diastatochromogenes
  • (1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-pyran]-3,9,13-trione
  • (1R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,27R,28S,29R)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonaMethyl-3',4',5',6'-tetrahydro-3H,9H,13H-spiro[2,26-dioxabicyclo[23.3.1]nonaco
  • MCH 32
  • AOligoMyci
  • mycin A
  • Oli
  • Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione,22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-,(1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16
  • Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,14,15-tetrahydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-, (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-
  • Oligomycin A MCH 32
  • Oligomycin A, >=98%
  • Oligomycin A, 99%, from Streptomyces diastatochromogenes
  • Oligomycin A from Streptomyces
  • OLIGOMYCIN A USP/EP/BP
  • (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-((R)-2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-2,26-dioxaspiro[bicyclo[23.3.1]nonacosa[4,18,20]triene-27,2'-pyran]-3,9,13-trione
  • (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-((R)-2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-2,26-dioxaspiro[bicyclo[23.3.1]nonacosa[4,18,20]triene-27,2'-
  • OLIGOMYCIN COMPLEX
  • CS-1898
  • (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14R,15S,16R,18E,20E,22R,25S,28S,29R)-22-Ethyl-7,11,14,15-tetrahydroxy-6'-((R)-2-hydroxypropyl)-5',6,8,10,12,14,16,28,29-nonamethyl-3',4',5',6'-tetrahydro-2,26-dioxaspiro[bicyclo[23.3.1]nonacosa[4,18,20]triene-27,2'-pyran]-3,9,13-trione
  • 579-13-5
  • Antibiotics
  • Antibiotics N-S
  • Antibiotics A to Z
  • BioChemical
  • Inhibitors
  • antibiotic
  • Antibiotics
  • AntifungalAntibiotics
  • Antineoplastic and Immunosuppressive AntibioticsAntibiotics
  • Inhibits an EnzymeAntibiotics
  • Antibiotics A to
  • Antibiotics by Application
  • Antibiotics N-SAntibiotics
  • Chemical Structure Class
  • Macrolides
  • Mechanism of Action
  • Spectrum of Activity
  • API
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