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N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonaMide

N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonaMide Struktur
380607-77-2
CAS-Nr.
380607-77-2
Englisch Name:
N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonaMide
Synonyma:
CMPDA;4-phenylene)bis(ethane-2;1-diyl))dipropane-2-sulfonaMide;N,N'-(1,4-Phenylenedi-2,1-ethanediyl)bis-2-propanesulfonamide;2-Propanesulfonamide, N,N'-(1,4-phenylenedi-2,1-ethanediyl)bis- (9CI);N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonaMide
CBNumber:
CB42729101
Summenformel:
C16H28N2O4S2
Molgewicht:
376.53
MOL-Datei:
380607-77-2.mol

N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonaMide Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
DMF: 30mg/mL; DMSO: 30mg/mL; Ethanol: 30mg/mL; PBS (pH 7.2): 10mg/mL
Aggregatzustand
Powder
Farbe
White to off-white

Sicherheit

N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonaMide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

CMPDA is a positive allosteric modulator of the ionotropic glutamate receptor GluA2. It increases glutamate-induced calcium influx into HEK293 cells expressing human GluA2i or GluA2o receptors (EC50s = 45.4 and 63.4 nM, respectively). CMPDA (10 μM) inhibits desensitization of rat GluA2o and GluA2i receptors, as well as slows the rate of deactivation of GluA2o, but not GluA2i, receptors, in HEK293 cells.

N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonaMide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonaMide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonaMide
  • CMPDA
  • N,N'-(1,4-Phenylenedi-2,1-ethanediyl)bis-2-propanesulfonamide
  • 1-diyl))dipropane-2-sulfonaMide
  • 4-phenylene)bis(ethane-2
  • 2-Propanesulfonamide, N,N'-(1,4-phenylenedi-2,1-ethanediyl)bis- (9CI)
  • 380607-77-2
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