RSC 133
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- CAS-Nr.
- 1418131-46-0
- Englisch Name:
- RSC 133
- Synonyma:
- RSC 133;RSC133,RSC 133;Reprogramming stimulating compound 133;3-[[(E)-3-(1H-indol-3-yl)prop-2-enoyl]amino]benzamide;3-[[(2E)-3-(1H-Indol-3-yl)-1-oxo-2-propen-1-yl]amino]-benzamide;Benzamide, 3-[[(2E)-3-(1H-indol-3-yl)-1-oxo-2-propen-1-yl]amino]-
- CBNumber:
- CB42708850
- Summenformel:
- C18H15N3O2
- Molgewicht:
- 305.33
- MOL-Datei:
- 1418131-46-0.mol
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RSC 133 Eigenschaften
- Siedepunkt:
- 653.7±55.0 °C(Predicted)
- Dichte
- 1.372±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- DMSO: soluble20mg/mL, clear
- pka
- 13.22±0.70(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to light brown
RSC 133 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
RSC-
133 is an indole compound that promotes the reprogramming of human somatic cells to pluripotent stem cells. Specifically, when used at 10 μM with four standard reprogramming factors, it increases the number of human foreskin fibroblasts that express the stem cell marker alkaline phosphatase. RSC-
133 induces pluripotency by both down-
regulating inducers of cellular senescence and inhibiting DNA methyltransferase and histone deacetylase activities.
Verwenden
RSC 133 is a potent chemical booster for human somatic cell reprogramming. RSC 133 facilitates the maintenance of pluripotent human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs).
RSC 133 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
RSC 133 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 33)Lieferanten
- RSC 133
- 3-[[(2E)-3-(1H-Indol-3-yl)-1-oxo-2-propen-1-yl]amino]-benzamide
- Reprogramming stimulating compound 133
- 3-[[(E)-3-(1H-indol-3-yl)prop-2-enoyl]amino]benzamide
- Benzamide, 3-[[(2E)-3-(1H-indol-3-yl)-1-oxo-2-propen-1-yl]amino]-
- RSC133,RSC 133
- 1418131-46-0
