GerMicidin A Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Germicidin A is a pyranone originally derived from
S. viridochromogenes that acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus
Streptomyces at concentrations as low as 200 pM. During germination, spores of
Streptomyces excrete germicidin A along with other germicidin homologs, which inhibit germination of its own arthrospores. At higher concentrations, germicidin A can inhibit the porcine Na
+/K
+-activated ATPase (ID
50 = 100 μM) and prevent the germination of the cress
L. sativum.
Verwenden
Germicidin A is a pyranone isolated from Streptomyces sp. in 1993. Germicidin A is an extremely potent autoregulator of the sporulation of the producing strain, and spores of closely related species. Inhibition is detected at 0.1 ng/ml and is orders of magnitude more potent than a diverse range of antibiotics.
GerMicidin A Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
