CRT-0066101
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- CAS-Nr.
- 956123-34-5
- Englisch Name:
- CRT-0066101
- Synonyma:
- CRT0066101;CRT 0066101;CRT-0066101;SCJXQZZYGYLKJG-CQSZACIVSA-N;Phenol, 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-;6-6-(2R)-2-Aminobutylamino-1H-pyrimidin-2-ylidene-4-(1-methylpyrazol-4-yl)cyclohexa-2,4-dien-1-one,hydrochloride
- CBNumber:
- CB42667706
- Summenformel:
- C18H22N6O
- Molgewicht:
- 338.41
- MOL-Datei:
- 956123-34-5.mol
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CRT-0066101 Eigenschaften
- Siedepunkt:
- 518.5±50.0 °C(Predicted)
- Dichte
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- Aggregatzustand
- powder
- pka
- 8.10±0.50(Predicted)
- Farbe
- white to beige
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Bildanzeige (GHS) |
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Alarmwort |
Warnung |
Gefahrenhinweise |
Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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Sicherheit |
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CRT-0066101 Chemische Eigenschaften,Einsatz,Produktion Methoden
Biochem/physiol Actions
CRT0066101 is a very potent inhibitor of Protein Kinase D (PKD) isoforms with IC50 values for PKD-1, -2 and -3 = 1, 2.5 and 2 nM, respecitively. CRT0066101 has been shown to have anticancer activity. CRT0066101 potently inhibits proliferation of PANC-1 pancreatic cells, and blocks migration and invasion of U87MG glioblastoma cells. CRT0066101 has also been shown to decrease growth of primary tumors and metastasis of ER(-) breast cancers.
CRT-0066101 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
CRT-0066101 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 26)Lieferanten
- CRT 0066101
- CRT0066101
- CRT-0066101
- SCJXQZZYGYLKJG-CQSZACIVSA-N
- 6-6-(2R)-2-Aminobutylamino-1H-pyrimidin-2-ylidene-4-(1-methylpyrazol-4-yl)cyclohexa-2,4-dien-1-one,hydrochloride
- Phenol, 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-
- 956123-34-5