CL 82198 HYDROCHLORIDE
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- CAS-Nr.
- 307002-71-7
- Englisch Name:
- CL 82198 HYDROCHLORIDE
- Synonyma:
- CL-82198
(CL82198;CL 82198 hydrochlori;CL 82198 HYDROCHLORIDE;N-(4-Morpholinobutyl)benzofuran-2-carboxamide;N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide;2-Benzofurancarboxamide, N-[4-(4-morpholinyl)butyl]-;CL-82198, Matrix metalloprotinase -13 (MMP-13) inhibitor;Benzofuran-2-carboxylic acid (4-morpholin-4-yl-butyl)-amide;N-(4-Morpholinobutyl)benzofuran-2-carboxamide hydrochloride;N-[4-(4-MORPHOLINYL)BUTYL]-2-BENZOFURANCARBOXAMIDE HYDROCHLORIDE
- CBNumber:
- CB42450342
- Summenformel:
- C17H22N2O3
- Molgewicht:
- 302.37
- MOL-Datei:
- 307002-71-7.mol
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CL 82198 HYDROCHLORIDE Eigenschaften
- Siedepunkt:
- 515.6±40.0 °C(Predicted)
- Dichte
- 1.159±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: >10mg/mL
- pka
- 14.19±0.46(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to off-white
- Stabilit?t:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 6 months.
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22 |
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| WGK Germany |
3 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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CL 82198 HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
CL 82,198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13), producing 89% inhibition at 10 μg/ml. It is without effect against MMP-1, MMP-9 or TNF-α converting enzyme. CL 82,198 is used to evaluate the role of MMP-13 in diverse processes, including cancer cell migration, acute lung injury, and joint degeneration associated with osteoarthritis.
Verwenden
CL-82198 is a selective inhibitor of human collagenase-3, known as matrix metalloproteinase-13.
Biologische Aktivit?t
Selective inhibitor of MMP-13 (89% inhibition at 10 μ g/mL) that displays no activity at MMP-1, MMP-9 or TACE. Inhibits in vitro invasion by the human pituitary adenoma cell line HP75.
CL 82198 HYDROCHLORIDE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
CL 82198 HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 56)Lieferanten
- CL 82198 HYDROCHLORIDE
- N-[4-(4-MORPHOLINYL)BUTYL]-2-BENZOFURANCARBOXAMIDE HYDROCHLORIDE
- N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide
- N-(4-morpholin-4-ylbutyl)-1-benzofuran-2-carboxamide,hydrochloride
- N-(4-Morpholinobutyl)benzofuran-2-carboxamide hydrochloride
- Benzofuran-2-carboxylic acid (4-morpholin-4-yl-butyl)-amide
- CL-82198
(CL82198
- 2-Benzofurancarboxamide, N-[4-(4-morpholinyl)butyl]-
- CL 82198 hydrochlori
- N-(4-Morpholinobutyl)benzofuran-2-carboxamide
- Inhibitor,CL-82198,CL82198,MMP,inhibit,Matrix metalloproteinases,CL 82198
- CL-82198, Matrix metalloprotinase -13 (MMP-13) inhibitor
- 307002-71-7
- C17H33N2O3HCl
- Protease inhibitor
- Angiogenesis and Metastasis
