4,4,5,5,5-Pentafluoro-1-pentanol
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- CAS-Nr.
- 148043-73-6
- Englisch Name:
- 4,4,5,5,5-Pentafluoro-1-pentanol
- Synonyma:
- 4,4,5,5,5-PENTAFLUOROPENTAN-1-OL;Pentafluoropentanol;4,4,5,5,5-PENTAFLUOROPENTANOL;Fulvestrant Impurity 31;Fulvestrant InterMediates;Fulvestrant intermediate C;4,4,5,5,5-PENTAFLUORO-1-PENTANOL;1,1,5,5,5-pentafluoro-1-pentanol;1-Pentanol,4,4,5,5,5-pentafluoro-;4,4,5,5,5-Pentafluoropentan-1-ol96%
- CBNumber:
- CB4232519
- Summenformel:
- C5H7F5O
- Molgewicht:
- 178.1
- MOL-Datei:
- 148043-73-6.mol
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4,4,5,5,5-Pentafluoro-1-pentanol Eigenschaften
- Siedepunkt:
- 62-64 °C35 mm Hg(lit.)
- Dichte
- 1.35 g/mL at 25 °C(lit.)
- Dampfdruck
- 1.1-155.2hPa at 25-80.3℃
- Brechungsindex
- n20/D 1.33(lit.)
- Flammpunkt:
- 145 °F
- storage temp.
- 2-8°C
- L?slichkeit
- Chloroform
- pka
- 14.77±0.10(Predicted)
- Aggregatzustand
- Liquid
- Farbe
- Clear colorless
- InChI
- InChI=1S/C5H7F5O/c6-4(7,2-1-3-11)5(8,9)10/h11H,1-3H2
- InChIKey
- QROUUECTKRZFHF-UHFFFAOYSA-N
- SMILES
- C(O)CCC(F)(F)C(F)(F)F
- LogP
- 1.59 at 25℃ and pH7
- CAS Datenbank
- 148043-73-6(CAS DataBase Reference)
- EPA chemische Informationen
- 3-(Perfluoroethyl)propanol (148043-73-6)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi,F |
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| R-S?tze: |
36-36/37/38 |
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| S-S?tze: |
26-36 |
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| RIDADR |
1993 |
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| WGK Germany |
2 |
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| Hazard Note |
Irritant |
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| HazardClass |
FLAMMABLE |
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| HS Code |
29055900 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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4,4,5,5,5-Pentafluoro-1-pentanol Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36:Reizt die Augen.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
4,4,5,5,5-Pentafluoro-1-pentanol (PFP; Pentafluoropentanol) is an essential building block primarily used in the commercial manufacture of the API. It is typically activated with a sulfonate leaving group and displaced selectively by the sulfur atom in 9-mercapto-1-nonanol to make 9-[(4,4,5,5,5-pentafluoropentyl)-thio]-1-nonanol (FVS). FVS is subsequently converted into a bromide and coupled with the steroid portion to make fulvestrant. First approved by the FDA in 2002, fulvestrant is a medication used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women with disease progression.
Chemische Eigenschaften
Colorless to yellow liquid
Verwenden
4,4,5,5,5-Pentafluoro-1-pentanol may be used in the preparation of chlorine-capped telechelic poly(methyl methacrylate)s.
Allgemeine Beschreibung
4,4,5,5,5-Pentafluoro-1-pentanol, also known as pentafluoropentanol, is a perfluorous solvent.
4,4,5,5,5-Pentafluoro-1-pentanol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4,4,5,5,5-Pentafluoro-1-pentanol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 299)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
|
Tianjin Huiren Chemtech Co., Ltd
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+86-86-22-23707858 +86-86-13672008665
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huirentech@foxmail.com |
China |
171 |
58 |
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Lewoo Pharmatech(Shanghai)Co.,Ltd
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+86-15800805830 +86-15800805830
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miao@lewoopharma.com.cn |
China |
184 |
58 |
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Liaoning Pharmaceutical Innovation Co., Ltd
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+8616588669988
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sales@pipharma.com.cn |
China |
151 |
58 |
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Hebei Zhuanglai Chemical Trading Co.,Ltd
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+8613343047651
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admin@zlchemi.com |
China |
3002 |
58 |
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Capot Chemical Co.,Ltd.
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+86-（0）57185586718 +86-13336195806
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sales@capot.com |
China |
29793 |
60 |
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Shanghai Daken Advanced Materials Co.,Ltd
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+86-371-66670886
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info@dakenam.com |
China |
18750 |
58 |
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Henan Tianfu Chemical Co.,Ltd.
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+86-0371-55170693 +86-19937530512
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info@tianfuchem.com |
China |
21634 |
55 |
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Hangzhou FandaChem Co.,Ltd.
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+8615858145714
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FandaChem@Gmail.com |
China |
8778 |
55 |
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Shanghai Yingrui Biopharma Co., Ltd.
|
+86-21-33585366 - 03@
|
sales03@shyrchem.com |
CHINA |
738 |
60 |
|
Fluoropharm Co., Ltd.
|
+86-0571-85586753; +8613336034509
|
sales@fluoropharm.com |
China |
1376 |
60 |
148043-73-6()Verwandte Suche:
- 4,4,5,5,5-PENTAFLUORO-1-PENTANOL
- 4,4,5,5,5-Pentafluoropentan-1-ol 96%
- 4,4,5,5,5-Pentafluoropentan-1-ol96%
- 4,4,5,5,5-Pentafluoro-1-pentanol,95%
- Fulvestrant InterMediates
- 1-Pentanol,4,4,5,5,5-pentafluoro-
- 4,4,5,5,5-Pentafluoro-1-pentanol 95%
- 4,4,5,5,5-Pentafluoro-1-pentanol ,97%
- 4,4,5,5,5-Pentafluoropentan-1-ol, tech
- 5-Hydroxy-1,1,1,2,2-pentafluoropentane, 3-(Perfluoroethyl)propan-1-ol
- Fulvestrant intermediate C
- Fulvestrant Impurity 31
- 1,1,5,5,5-pentafluoro-1-pentanol
- 4,4,5,5,5-pentafluoropentyl alcohol
- 4,4,5,5,5-Pentafluoro-1-pentanol>
- 4,4,5,5,5-Pentafluoro-1-pentanol(For export only)
- 4,4,5,5,5-PENTAFLUOROPENTAN-1-OL
- 4,4,5,5,5-PENTAFLUOROPENTANOL
- Pentafluoropentanol
- 148043-73-6
- 148-043-6
- C5H7F5O
- C2F5CH2CH2CH2OH
- CF3CF2CH23OH
- Organic Building Blocks
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- Building Blocks
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