(S)-1-(Hydroxymethyl)ethan-1,2-diyldipalmitat
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(S)-1-(Hydroxymethyl)ethan-1,2-diyldipalmitat Eigenschaften
- Schmelzpunkt:
- 66-69 °C
- Siedepunkt:
- 620.8±22.0 °C(Predicted)
- Dichte
- 0.930±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- DMF: 20 mg/ml; DMSO: 5 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): .25 mg/ml
- Aggregatzustand
- A crystalline solid
- pka
- 13.69±0.10(Predicted)
- Farbe
- White to off-white
- BRN
- 1730209
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
WGK Germany | 1 | ||
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F | 10 |
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(S)-1-(Hydroxymethyl)ethan-1,2-diyldipalmitat Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
1,2-Dipalmitoyl-sn-glycerol (1,2-DPG) is an analog of the protein kinase C (PKC)-activating second messenger diacylglycerol. 1,2-Dipalmitoyl-sn-glycerol is a weak activator of PKC.Definition
ChEBI: A 1,2-diacyl-sn-glycerol in which both acyl groups are specified as palmitoyl (hexadecanoyl).Allgemeine Beschreibung
In biochemical signaling, diacylglycerol (DAG) functions as a second messenger signaling lipid, and is a product of the hydrolysis of the phospholipid PIP2 (phosphatidylinositolbisphosphate) by the enzyme phospholipase C (PLC) (a membrane-bound enzyme) that, through the same reaction, produces inositol trisphosphate (IP3). Although inositol trisphosphate (IP3) diffuses into the cytosol, DAG remains within the plasma membrane due to its hydrophobic properties. IP3 stimulates the release of calcium ions from the smooth endoplasmic reticulum, whereas DAG is a physiological activator of protein kinase C (PKC). The production of DAG in the membrane facilitates translocation of PKC from the cytosol to the plasma membrane.Diacylglycerol mimicks the effects of the tumor-promoting compounds phorbol esters.
l?uterung methode
Crystallise S(-)-1,2-dipalmitin from chloroform/pet ether (b 40-60o) ~1:1.5. [S(-)-isomer: Baer & Kates J Am Chem Soc 72 942 1950, Hanahan & Vercamer J Am Chem Soc 7 6 1804 1954, R(+)-isomer: Tattrie et al. Arch Biochem 78 319 1958, Beilstein 2 IV 1173.] The racemate [40290-32-2] is polymorphic with different IR spectra. When crystallised from hexane, or other solvents, the higher melting form with m 71.5-72.5o is obtained. The melt then solidifies to give the lower melting -form with m 49.7-50o. The -form has m 61o (65-66o is also reported). When the lower melting forms are kept at their melting temperatures for a while, they are converted to the higher melting form. [Howe & Malkin J Chem Soc 2663 1951, Baer & Kates J Am Chem Soc 72 942 1950, Beilstein 2 IV 1173.](S)-1-(Hydroxymethyl)ethan-1,2-diyldipalmitat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(S)-1-(Hydroxymethyl)ethan-1,2-diyldipalmitat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 91)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-18789408387 |
1057@dideu.com | China | 3958 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32070 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52849 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 |
sales@nextpeptide.com | China | 19908 | 58 |
Alfa Chemistry | |
Info@alfa-chemistry.com | United States | 24072 | 58 |
TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38463 | 58 |
PT CHEM GROUP LIMITED | |
peter68@ptchemgroup.com | China | 35425 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 49979 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20288 | 58 |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 |
cooperation@kean-chem.com | China | 40066 | 58 |
30334-71-5((S)-1-(Hydroxymethyl)ethan-1,2-diyldipalmitat)Verwandte Suche:
Palmitinsure
Glycerindipalmitat
Glycerintristearat
Glycerintripalmitat
(R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid
Propan-1,2,3-triyltriicosanoat
(R)-(7-Lauroyl-4-oxido-10-oxo-3,5,9-trioxa-4-phosphaheptacosyl)trimethylammonium-4-oxid
Propan-1,2,3-triyltridocosanoat
(R)-1-[[[(2-Aminoethoxy)hydroxyphosphinoyl]oxy]methyl]ethan-1,2-diyldihexadecanoat
2-Hydroxypropan-1,3-diyldipalmitat
(R)-1-(3-Hydroxy-7-methyl-2,4-dioxa-7-aza-3-phosphaoct-1-yl)ethylendipalmitat-P-oxid
(R)-1-[[[(2-Aminoethoxy)hydroxyphosphinyl]oxy]methyl]ethan-1,2-diyldistearat
(R)-1-(3-Hydroxy-2,4-dioxa-7-aza-3-phosphaoct-1-yl)ethylendipalmitat-P-oxid
2,3-Bis(palmitoyloxy)propyldihydrogenphosphat
- D-ALPHA,BETA-DIPALMITIN
- L-1,2-DIPALMITOYLGLYCEROL
- 16:0 DG
- 1,2-DIPALMITOYL-SN-GLYCEROL
- 1,2-DIPALMITOYL-SN-3-GLYCEROL
- 1,2-DIHEXADECANOYL-SN-GLYCEROL
- (S)-1,2-DIPALMITIN
- (S)-GLYCEROL 1,2-DIPALMITATE
- (S)-1-(hydroxymethyl)ethane-1,2-diyl dipalmitate
- 1,2-DIPALMITOYL-SN-GLYCEROL (C16:0)
- (S)-1-(Hydroxymethyl)ethan-1,2-diyldipalmitat
- L-1,2-DIPALMITOYLGLYCEROL synthetic
- Einecs 250-131-4
- 1,2-Di-O-palMitoyl-sn-glycerol
- Hexadecanoic Acid 1,1'-[(1S)-1-(HydroxyMethyl)-1,2-ethanediyl] Ester
- NSC 269964
- sn-1,2-DipalMitin
- D-a,b-DipalMitin
- (S)-1,2-Dipalmitin, (S)-Glycerol 1,2-dipalmitate, 1,2-Dihexadecanoyl-sn-glycerol
- (-)-L-1,2-Dipalmitin
- (S)-Propane-1,2,3-triol 1,2-dipalmitate
- 1-O,2-O-Dipalmitoyl-L-glycerol
- Bishexadecanoic acid (S)-3-hydroxypropane-1,2-diyl ester
- Bispalmitic acid (S)-3-hydroxypropane-1,2-diyl ester
- (-)-1,2-di-O-hexadecanoyl-sn-glycerol
- DipalMitoyl-sn-glycerol L-0016
- 1,2-DIPALMITOYL-SN-GLYCEROL, >=99%
- 1,2-Dipalmitin-sn-glycerol
- DPG
- 1,2-DIPALMITIN
- DG(16:0/16:0/0:0)
- (S)-3-Hydroxypropane-1,2-diyl dipalmitate
- Endogenous Metabolite,1,2Dipalmitoylsnglycerol,1,2 Dipalmitoyl sn glycerol,inhibit,Inhibitor
- (2S)-2-hexadecanoyloxy-3-hydroxypropyl] hexadecanoate
- 30334-71-5
- Neutral Glycerides
- Lipids
- Glycerides
- Diradylglycerols
- Biochemicals and Reagents
- BioChemical
- Fatty & Aliphatic Acids, Esters, Alcohols & Derivatives
- Aliphatics
- Fatty Acid Derivatives & Lipids
- Glycerols
- Protein Kinase Inhibitors and Activators