5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide
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- CAS-Nr.
- 868273-06-7
- Englisch Name:
- 5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide
- Synonyma:
- CS-412;Org 27569;ORG 27569;ORG-27569;Org27569 Cannabinoid CB1 receptor allosteric modulator Org-27569;Org27569,Inhibitor,Org-27569,Cannabinoid Receptor,Org 27569,inhibit;N-(4-(piperidin-1-yl)phenethyl)-5-chloro-3-ethyl-1H-indole-2-carboxamide;5-Chloro-3-ethyl-N-(4-(piperidin-1-yl)phenethyl)-1H-indole-2-carboxamide;5-Chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl-1H-indole-2-carboxamide;1H-Indole-2-carboxamide,5-chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl]-;Org27569 5-Chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl-1H -indole-2-carboxamide
- CBNumber:
- CB42092872
- Summenformel:
- C24H28ClN3O
- Molgewicht:
- 409.95
- MOL-Datei:
- 868273-06-7.mol
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5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide Eigenschaften
- Siedepunkt:
- 660.3±55.0 °C(Predicted)
- Dichte
- 1.218±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: <2mg/mL
- pka
- 14.87±0.30(Predicted)
- Aggregatzustand
- powder
- Farbe
- white
Sicherheit
Kennzeichnung gef?hrlicher |
Xn |
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R-S?tze: |
22 |
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WGK Germany |
3 |
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5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
Verwenden
Org 27569 is a drug that is a used in biological studies for structure-activity relationships of indole-carboxamides as CB1 receptor allosteric modulators.
Biologische Aktivit?t
Potent CB 1 receptor allosteric modulator (pEC 50 = 8.24). Significantly increases binding of the CB 1 agonist [ 3 H]CP 55.940 (pK b = 5.67) and decreases binding of the CB 1 inverse agonist [ 3 H]SR 141716A (pK b = 5.95). Inhibits CB 1 receptor antagonist efficacy in vitro (pK b = 7.57).
5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 74)Lieferanten
868273-06-7()Verwandte Suche:
- 5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide
- Org 27569
- Org27569 5-Chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl-1H -indole-2-carboxamide
- 5-Chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl-1H-indole-2-carboxamide
- 1H-Indole-2-carboxamide,5-chloro-3-ethyl-N-[2-[4-(1-piperidinyl)phenyl]ethyl]-
- 5-Chloro-3-ethyl-N-(4-(piperidin-1-yl)phenethyl)-1H-indole-2-carboxamide
- N-(4-(piperidin-1-yl)phenethyl)-5-chloro-3-ethyl-1H-indole-2-carboxamide
- ORG 27569;ORG-27569
- 5-chloro-3-ethyl-1H-indole-2-carboxylic acid [2-(4-piperidin-1-yl-phenyl)-ethyl]-amide USP/EP/BP
- CS-412
- Org27569 Cannabinoid CB1 receptor allosteric modulator Org-27569
- Org27569,Inhibitor,Org-27569,Cannabinoid Receptor,Org 27569,inhibit
- 868273-06-7
- Inhibitors