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Ataciguat

Ataciguat Struktur
254877-67-3
CAS-Nr.
254877-67-3
Englisch Name:
Ataciguat
Synonyma:
HMR 1766;Ataciguat;Ataciguat (HMR-1766;Ataciguat, 10 mM in DMSO;5-Chloro-2-(5-chlorothiophene-2-sulfonamido)-N-(4-(morpholinosulfonyl)phenyl)benzamide;5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide;Benzamide, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-;cyclase,soluble,HMR 1766,Ataciguat,Guanylate Cyclase,Inhibitor,sGC,inhibit,HMR1766,vasodilator,cGMP,guanylate
CBNumber:
CB41565384
Summenformel:
C21H19Cl2N3O6S3
Molgewicht:
576.5
MOL-Datei:
254877-67-3.mol

Ataciguat Eigenschaften

Dichte
1.613±0.06 g/cm3(Predicted)
L?slichkeit
DMF: 1 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml
Aggregatzustand
A crystalline solid
pka
5.70±0.50(Predicted)
Farbe
White to off-white

Sicherheit

Ataciguat Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Ataciguat, formerly referred to as HMR-1766, a novel anthranilic acid derivative, belongs to a new structural class of sGC activators capable of activating the oxidized form of sGC. Ataciguat has been shown to improve endothelial function and to reduce platelet activation in exptl. diabetes. Chronic regular treatment with sGC activators such as ataciguat could therefore eventually constitute an effective therapy targeting deficient NO/cGMP signaling in hypertension, peripheral and coronary artery disease, heart failure, thrombosis and erectile dysfunction.

Ataciguat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Ataciguat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 57)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
Shanghai Boyle Chemical Co., Ltd.
sales@boylechem.com China 2922 55
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 96815 76
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15402 60
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979
info@tsbiochem.com China 8065 58
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189
 mychess007@163.com China 1994 55
SPIRO PHARMA
eric_feng1954@126.com China 9248 55
  • 5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide
  • Ataciguat
  • HMR 1766
  • Benzamide, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-
  • Ataciguat (HMR-1766
  • cyclase,soluble,HMR 1766,Ataciguat,Guanylate Cyclase,Inhibitor,sGC,inhibit,HMR1766,vasodilator,cGMP,guanylate
  • 5-Chloro-2-(5-chlorothiophene-2-sulfonamido)-N-(4-(morpholinosulfonyl)phenyl)benzamide
  • Ataciguat, 10 mM in DMSO
  • 254877-67-3
  • C21H19Cl2N3O6S3
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
  • Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
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