Lexithromycin
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Lexithromycin Eigenschaften
- Schmelzpunkt:
- >115°C (dec.)
- Siedepunkt:
- 824.6±75.0 °C(Predicted)
- Dichte
- 1.26±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- L?slichkeit
- Chloroform (Slightly), DMSO (Slightly)
- pka
- 13.19±0.70(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- Stabilit?t:
- Hygroscopic
Sicherheit
Lexithromycin Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Lexithromycin is a semisynthetic antibiotic derived from erythromycin . Lexithromycin has improved absorption in vivo over erythromycin due to increased hydrophopicity and pH stability. As with other macrolides, lexithromycin prevents protein synthesis by binding the ribosome at the polypeptide exit tunnel. Formulations containing lexithromycin were tested in clinical trials as treatment for HIV but were discontinued.Verwenden
Lexithromycin is an early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime. The structural change improves the pH stability profile and hydrophobicity of lexithromycin for better in vivo absorption. This same rationale was used to greater effect with roxithromycin and, as a result, lexithromycin was quickly superseded and has not been not extensively studied. Like all tetracyclines, lexithromycin shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.Lexithromycin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Lexithromycin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 45)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14332 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23541 | 58 |
BOC Sciences | 16314854226; +16314854226 |
inquiry@bocsci.com | United States | 19741 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6391 | 58 |
China National Standard Pharmaceutical Corporation Limited | +8615391658522 |
overseasales@yongstandards.com | China | 11922 | 58 |
Moxin Chemicals | +8617320513646 |
mike@molcoo.com | China | 9546 | 58 |
S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-4000505016 13380397412 |
3001272453@qq.com | China | 5047 | 50 |
ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 |
sales@chem-strong.com | China | 18070 | 56 |
Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 |
greensnown@163.com | China | 9906 | 50 |
- erythromycin A methoxime
- 9-(Methoxyimino)-9-deoxoerythromycin
- 9-Deoxo-9-[[methyloxy]imino]erythromycin
- ErythroMycin A 9-MethoxiMe, Wy 48314
- Erythromycin A-E-oxime
- Erythromycin A-E-oxime LEXITHROMYCIN.
- Lexithromycin
- Erythromycin A 9-Methoxime
- Azithromycin Impurity 4
- Azithromycin Impurity 31
- Wy 48314
- Erythromycin, 9-(O-methyloxime)
- 53066-26-5