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(R*,S*)-(±)-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]chinolin-2(1H)-onmonohydrochlorid

PROCATEROL HYDROCHLORIDE Struktur
62929-91-3
CAS-Nr.
62929-91-3
Bezeichnung:
(R*,S*)-(±)-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]chinolin-2(1H)-onmonohydrochlorid
Englisch Name:
PROCATEROL HYDROCHLORIDE
Synonyma:
meptin;opc2009;Epcalol;Cateptin;Astoprotin;Carvedilol-d;PROCATEROL HCL;Einecs 263-763-0;Aficamten Impurity 26;Procaterol hydrochlorid
CBNumber:
CB4120391
Summenformel:
C16H23ClN2O3
Molgewicht:
326.82
MOL-Datei:
62929-91-3.mol

(R*,S*)-(±)-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]chinolin-2(1H)-onmonohydrochlorid Eigenschaften

storage temp. 
2-8°C
L?slichkeit
Soluble to 100 mM in water and to 100 mM in DMSO
Aggregatzustand
Powder
Stabilit?t:
Hygroscopic
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  2
RTECS-Nr. VC8296000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H361 Kann vermutlich die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. Reproduktionstoxizit?t Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P281 Vorgeschriebene pers?nliche Schutzausrüstung verwenden.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

(R*,S*)-(±)-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]chinolin-2(1H)-onmonohydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Procaterol is an agonist of β2-adrenergic receptors (β2-ARs). It binds to (Kd = 46 pM), and is selective for, β2-ARs over β1-ARs (Kd = 4,000 pM). Procaterol binds more potently to β2-ARs in isolated guinea pig lung than to β1-ARs in isolated guinea pig cardiac ventricle in the presence (IC50s = 175 and 1,660 nM, respectively) and absence of GTP (; IC50s = 55.1 and 1,660 nM, respectively). It inhibits contractions induced by acetylcholine in isolated guinea pig trachea (EC50 = 10.5 nM). In vivo, procaterol inhibits histamine-induced airflow obstruction in a guinea pig model of ovalbumin-sensitized asthma when administered via inhalation at a dose of 10 μg/ml.

Verwenden

Procaterol Hydrochloride is a short-acting pulmonary β2-agonist for asthma treatment.

Allgemeine Beschreibung

Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.

Biologische Aktivit?t

Specific and very potent β 2 agonist.

(R*,S*)-(±)-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]chinolin-2(1H)-onmonohydrochlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(R*,S*)-(±)-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]chinolin-2(1H)-onmonohydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 79)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
career henan chemical co 		+86-0371-86658258 +8613203830695
 sales@coreychem.com China 29871 58
Xiamen AmoyChem Co., Ltd 		+86-86-5926051114 +8618959220845
 sales@amoychem.com China 6383 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873
 sales@chemdad.com China 39894 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49476 58
SIMAGCHEM CORP 		+86-13806087780
 sale@simagchem.com China 17365 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763
 sales@tnjchem.com China 34563 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250
 1026@dideu.com China 22787 58
LEAP CHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 24727 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581
 sales@chemhifuture.com China 3135 58

62929-91-3((R*,S*)-(±)-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]chinolin-2(1H)-onmonohydrochlorid)Verwandte Suche:

  • Procaterol hydrochlorid
  • erythro-8-hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-2(1h)-quinolinone
  • 2(1H)-Quinolinone, 8-hydroxy-5-[(1R,2S)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride, rel- (9CI)
  • 2(1H)-Quinolinone, 8-hydroxy-5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride, (R*,S*)-
  • 2(1H)-Quinolinone, 8-hydroxy-5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-, monohydrochloride, (R*,S*)-(+-)-
  • PROCATEROL HCL
  • 5-(1-hydroxy-2-isopropylamino)butyl-8-hydroxycarbostyrilhydrochloride
  • 8-hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1h)-quinolinonmono
  • meptin
  • opc2009
  • (R*,S*)-(±)-8-hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]quinolin-2(1H)-one monohydrochloride
  • Astoprotin
  • Cateptin
  • Epcalol
  • (R*,S*)-(1)-8-Hydroxy-5-(1-hydroxy-2-(isopropylamino)butyl)quinolin-2(1H)-one monohydrochloride
  • Einecs 263-763-0
  • rel-8-Hydroxy-5-[(1R,2S)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-2(1H)quinolinone hydrochloride
  • (+/-)-ERYTHRO-8-HYDROXY-5-[1-HYDROXY-2-(ISOPROPYLAMINO)BUTYL]CARBOSTYRIL HYDROCHLORIDE
  • 8-HYDROXY-5-(1-HYDROXY-2-PROPAN-2-YLAMINO-BUTYL)-1H-QUINOLIN-2-ONE
  • Procaterol hydrochloride Solution, 100ppm
  • Procaterol hydrochloride Solution, 1000ppm
  • Procaterol HCl,Procaterol hydrochloride
  • 8-hydroxy-5-[1-hydroxy-2-(propan-2-ylamino)butyl]-1H-quinolin-2-one hydrate hydrochloride
  • Carvedilol-d
  • Aficamten Impurity 26
  • Procaterol hydrochloride, beta2 adrenoceptor agonist
  • 62929-91-3
  • C16H22N2O3HClH2O
  • Adrenoceptor
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