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6-AMINO-N-CYCLOHEXYL-N,3-DIMETHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE

6-AMINO-N-CYCLOHEXYL-N,3-DIMETHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE Struktur
748758-45-4
CAS-Nr.
748758-45-4
Englisch Name:
6-AMINO-N-CYCLOHEXYL-N,3-DIMETHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE
Synonyma:
YM 298198 HYDROCHLORIDE;Thiazolo[3,2-a]benzimidazole-2-carboxamide,6-amino-N-cyclohexyl-N,3-dimethyl-;6-amino-N-cyclohexyl-N,3-dimethylbenzo[4,5]imidazo[2,1-b]thiazole-2-carboxamide;6-AMINO-N-CYCLOHEXYL-N,3-DIMETHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE
CBNumber:
CB3838194
Summenformel:
C18H22N4OS
Molgewicht:
342.46
MOL-Datei:
748758-45-4.mol

6-AMINO-N-CYCLOHEXYL-N,3-DIMETHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE Eigenschaften

storage temp. 
Desiccate at +4°C
Wasserl?slichkeit
Soluble in water (100mM)

Sicherheit

6-AMINO-N-CYCLOHEXYL-N,3-DIMETHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Aktivit?t

Non-competitive antagonist with high affinity and selectivity for mGlu 1 receptors (K i = 19 nM); inactive at other mGlu receptor subtypes (mGlu 2-7 ), ionotropic receptors and glutamate transporters (IC 50 > 10 μ M). Inhibits glutamate-induced IP production more potently than CPCCOEt (IC 50 values are 16 nM and 6.3 μ M respectively), and is orally active in vivo , demonstrating an antinociceptive effect in hyperalgesic mice.

6-AMINO-N-CYCLOHEXYL-N,3-DIMETHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


6-AMINO-N-CYCLOHEXYL-N,3-DIMETHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 20)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15839 69
Ascent Scientific 4401179829988
customerservice@ascentscientific.co.uk United Kingdom 279 60
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216
info@yuhaochemical.com China 2028 58
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44918 58
JinOu Biomedical (Nanjing) Co., Ltd. 13000000000
jinoupharma@163.com China 11721 58

  • 6-AMINO-N-CYCLOHEXYL-N,3-DIMETHYLTHIAZOLO[3,2-A]BENZIMIDAZOLE-2-CARBOXAMIDE HYDROCHLORIDE
  • YM 298198 HYDROCHLORIDE
  • 6-amino-N-cyclohexyl-N,3-dimethylbenzo[4,5]imidazo[2,1-b]thiazole-2-carboxamide
  • Thiazolo[3,2-a]benzimidazole-2-carboxamide,6-amino-N-cyclohexyl-N,3-dimethyl-
  • 748758-45-4
  • C18H22N4OSHCl
  • Glutamate receptor
  • Glutamate
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