(SAR9,MET(O2)11)-SUBSTANCE P
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- CAS-Nr.
- 110880-55-2
- Englisch Name:
- (SAR9,MET(O2)11)-SUBSTANCE P
- Synonyma:
- Bhsar-sp;Bhsar-sp|||NA;[Sar9, Met(O2)11;[Sar9]SP sulfone;RPKPQQFFSARLM(O2);[Sar9]SP sulphone;[Sar9,Met(O2)11]SP;9-Sar-substance p sulfone;[Sar9]substance P sulphone;9-Sar-11-Met(o2)-substance p
- CBNumber:
- CB3758823
- Summenformel:
- C64H100N18O15S
- Molgewicht:
- 1393.66
- MOL-Datei:
- 110880-55-2.mol
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(SAR9,MET(O2)11)-SUBSTANCE P Eigenschaften
- Dichte
- 1.43±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- L?slichkeit
- H2O : 50 mg/mL (35.88 mM; Need ultrasonic)
- pka
- 13.31±0.20(Predicted)
- Aggregatzustand
- Lyophilized solid.
- Farbe
- White to off-white
- Wasserl?slichkeit
- Soluble to 1 mg/ml in water
- Sequenz
- H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met(O2)-NH2
Sicherheit
(SAR9,MET(O2)11)-SUBSTANCE P Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
[Sar9,Met(O2)11]-Substance P is a potent and selective NK1 tachykinin receptor agonist (1). The NK1 tachykinin receptor is a member of the G-protein coupled receptor family and can be found in neurons, brainstem, and vascular endothelial cells (2,3). NK1 tachykinin receptor is a therapeutic target for pancreatic cancer (4).
Biochem/physiol Actions
Highly selective NK-1 receptor agonist.
(SAR9,MET(O2)11)-SUBSTANCE P Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(SAR9,MET(O2)11)-SUBSTANCE P Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 106)Lieferanten
110880-55-2()Verwandte Suche:
- H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-SAR-LEU-MET(O2)-NH2
- ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-SAR-LEU-MET(O2)-NH2
- (SAR9,MET(O2)11)-SUBSTANCE P
- RPKPQQFFSARLM(O2)
- [SAR9 ,MET(O2 )11 ]-SUBSTANCE P HIGHLY SPECIFIC NEUROKININ NK1 RECEPTOR 97+%
- [Sar9,met(o2)11]-substancephighlyspecificneurokininnk1receptor
- substance P, Sar(9)-Met(O2)(11)-
- [Sar9, Met(O2)11
- 9-Sar-11-Met(o2)-substance p
- 9-Sarcosyl-11-methionine(o2)-substance p
- 9-Sar-substance p sulfone
- Bhsar-sp
- Bolton hunter-9-sar-11-Met(02)-substance p
- Bolton-hunter reagent-substance p. sar(9)-Met(02)(11)
- Sarcosyl(9)-substance p sulfone
- [Sar9,Met(O2)11]SP
- [Sar9]SP sulfone
- [Sar9]SP sulphone
- [Sar9]substance P sulphone
- L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-L-Phe-Sar-L-Leu-4-(Methylsulfonyl)-L-Abu-NH2
- (2S)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfonyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1,5-dioxopentan-2-yl]pentanediamide
- [Sar9,Met(O2)11]-Substance P,Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met[O2]-NH2?, >98%
- [SAR9,MET(O2)11]-SUBSTANCE P?, >98%
- Substance P, 9-(N-methylglycine)-, S,S-dioxide
- (SAR9,MET(O2)11)-SUBSTANCE P USP/EP/BP
- Inhibitor,Tachykinin receptor,[Sar9,Met(O2)11]-Substance P,NK receptor,Neurokinin Receptor,[Sar9,Met(O2)11] Substance P,[Sar9,Met(O2)11]Substance P,inhibit,[Sar-9,Met(O2)11]-Substance P
- Substance p,9-(N-methylglycine)-11-(s,s-dioxido-L-methioninamide)-
- (Sar?,Met(O?)??)-Substance P
- Bhsar-sp|||NA
- 110880-55-2
- C64H100N18O15S
- C64H97N19O15S
- BioChemical
- Amino Acids and Peptides
- Agonist
- Biochemicals and Reagents
- Peptides
- Tachykinins
- Tachykinin receptor