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NEUROPEPTIDE FF

NEUROPEPTIDE FF Struktur
99566-27-5
CAS-Nr.
99566-27-5
Englisch Name:
NEUROPEPTIDE FF
Synonyma:
NPFF;NPAF;ninamide;F-8-F-NH2;FLFQPQRF-NH2;NEUROPEPTIDE FF;Neuropeptide FF TFA;Neuropeptide FF (cattle);Neuropeptide FF F-8-F-NH2;NEUROPEPTIDE FF USP/EP/BP
CBNumber:
CB3750458
Summenformel:
C54H76N14O10
Molgewicht:
1081.27
MOL-Datei:
99566-27-5.mol

NEUROPEPTIDE FF Eigenschaften

storage temp. 
−20°C
L?slichkeit
Water: 1 mg/ml
Aggregatzustand
Solid
Farbe
White to off-white
Wasserl?slichkeit
Soluble to 0.50 mg/ml in water.

Sicherheit

WGK Germany  3

NEUROPEPTIDE FF Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Neuropeptide FF (NPFF) is a peptide expressed in the brain and spinal cord that shares a precursor protein with neuropeptide AF. NPFF is expressed primarily in the posterior pituitary, hypothalamus, and medulla. It is an agonist at NPFF1 and NPFF2 receptors (Kis = 2.82 and 0.21 nM, respectively, for human recombinant receptors) that inhibits forskolin-induced cAMP production in CHO cells (EC50s = 236 and 2.3 nM, respectively). NPFF activates parvocellular neurons in the paraventricular nucleus (PVN) of the hypothalamus to stimulate oxytocin release from their projections in the brain stem, thereby regulating baroreflex control of heart rate. However, it inhibits magnocellular PVN neurons by enhancing GABAergic input. It is also found in plasma and exogenous administration briefly increases mean arterial pressure (MAP) by 40 mm Hg in rats, an effect that is only partially blocked by the norepinephrine competitor guanethidine and the α1-adrenergic receptor antagonist prazosin . NPFF has anti-opioid effects in rodent models, inhibiting morphine-induced analgesia and inducing abstinence in morphine-tolerant rats. It also inhibits acquisition of conditioned place preference to cocaine in rats when administered at doses of 10 and 20 nmol.

Verwenden

Endogenous antiopioid peptide and agonist at NPFF1 and NPFF2 receptors (Ki values are 2.82 and 0.21 nM respectively). Exhibits anorexigenic effects.

NEUROPEPTIDE FF Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


NEUROPEPTIDE FF Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 104)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715
admin@nexconn.com China 10311 58
Cellmano Biotech Limited
0551-65326643 18156095617
info@cellmano.com China 999 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29810 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22787 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19741 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
Hangzhou Go Top Peptide Biotech
0571-88211921
sales1@gotopbio.com CHINA 2609 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634
Cecilia@youngshechem.com China 2345 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490
info@gihichemicals.com China 49978 58

99566-27-5()Verwandte Suche:


  • PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE AMIDE
  • PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2
  • NPFF
  • NEUROPEPTIDE FF
  • H-PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2
  • F-8-F-NH2
  • ninamide
  • phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylala
  • POTASSIUM FERROCYANIDE TRIHYDRATE*ACS RE AGENT
  • Neuropeptide FF F-8-F-NH2
  • phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide
  • Neuropeptide FF Morphine Modulating Neuropeptide F-8-F-NH2
  • Neuropeptide FF F-8-F-NH2, NPFF, F-8-F-aMide
  • F-8-F-NH2, NPFF, F-8-F-aMide
  • ANTI-NPFF (C-TERM) antibody produced in rabbit
  • FMRFamide-related peptides
  • NPAF
  • Neuropeptide FF (trifluoroacetate salt)
  • L-Phenylalaninamide, L-phenylalanyl-L-leucyl-L-phenylalanyl-L-glutaminyl-L-prolyl-L-glutaminyl-L-arginyl-
  • Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe amide >=95% (HPLC)
  • NEUROPEPTIDE FF USP/EP/BP
  • Neuropeptide FF (cattle)
  • FLFQPQRF-NH2
  • Neuropeptide FF trifluoroacetate salt (NPFF)
  • Neuropeptide FF TFA
  • Rabbit Anti-NPFF antibody
  • 99566-27-5
  • C54H76N14O10
  • BioChemical
  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • Other Peptides
  • Peptides
  • Peptide
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