NOBILETIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
White powder
Verwenden
Nobiletin is an O-methylated flavone, a flavonoid isolated from citrus peels like in tangerine. It is a potent antioxidant with good bioavailability. Nobiletin directly inhibits the ATP-binding cassette proteins P-glycoprotein and breast cancer resistance protein.
Definition
ChEBI: A methoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 8, 3' and 4' respectively.
benefits
Nobiletin improved cognitive deficits and the pathological features of AD, such as Aβ pathology, hyperphosphorylation of tau, and oxidative stress, in animal models of AD. In addition, nobiletin improved motor and cognitive deficits in PD animal models. These observations suggest that nobiletin has the potential to become a novel drug for the treatment and prevention of neurodegenerative diseases such as AD and PD.
NOBILETIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Phenol, 2,3,4-trimethoxy-, 1-formate
1,2,3,4-TETRAMETHOXYBENZENE
1,3-Propanedione, 1-(3,4-dimethoxyphenyl)-3-(2-hydroxy-3,4,5,6-tetramethoxyphenyl)-
4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,8-dihydroxy-6,7-dimethoxy-
1-(3,4-dimethoxybenzoyl)-1H-1,2,3-benzotriazole
Phenol, 2,3,4,5-tetramethoxy-
1-(2-hydroxy-3,4,6-trimethoxy-phenyl)ethanone
1-(2-hydroxy-3,4,5,6-tetramethoxyphenyl)ethanone
Pentamethoxybenzene
1,2,3,5-TETRAMETHOXYBENZENE
Veratroylchlorid
2,3,4-Trimethoxybenzaldehyd
Veratrumsure
1,2,3-Trimethoxybenzol
Downstream Produkte