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Clindamycin palmitate hydrochloride

Clindamycin palmitate hydrochloride Struktur
25507-04-4
CAS-Nr.
25507-04-4
Englisch Name:
Clindamycin palmitate hydrochloride
Synonyma:
Clindmycin;Cleocin Pediatric;Clindamycin Impurity 85;CLINDAMYCIN PALMITATE HCL;Clindamycin 2-Palmitate HCl;ClindaMycin PalMitate HCl USP;Clindamycin Hydrochloride Palmitate;Clindamycin palmitate hydrochloride;clindamycin2’-palmitatehydrochloride;Clindamycin Palmitate Hydrochloride (USP)
CBNumber:
CB3666368
Summenformel:
C34H64Cl2N2O6S
Molgewicht:
699.85
MOL-Datei:
25507-04-4.mol

Clindamycin palmitate hydrochloride Eigenschaften

Schmelzpunkt:
141-143°C
storage temp. 
-20°C Freezer, Under Inert Atmosphere
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
Farbe
White to Off-White
InChIKey
GTNDZRUWKHDICY-ZLNNALEKSA-N
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
HS Code  2941906000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

Clindamycin palmitate hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Clindamycin palmitate is a water-soluble prodrug form of the antibiotic clindamycin . It undergoes rapid hydrolysis in vivo to release active clindamycin. Formulations containing clindamycin palmitate have been used in the treatment of various bacterial infections.

Chemische Eigenschaften

White Solid

Verwenden

antibacterial (tuberculostatic)

Allgemeine Beschreibung

Clindamycin palmitate hydrochloride (Cleocin Pediatric) isthe hydrochloride salt of the palmitic acid ester ofcleomycin. The ester bond is to the 2-hydroxyl group of thelincosamine sugar. The ester serves as a tasteless prodrugform of the antibiotic, which hydrolyzes to clindamycin inthe plasma. The salt form confers water solubility to theester, which is available as granules for reconstitution intoan oral solution for pediatric use. Although absorption of thepalmitate is slower than that of the free base, there is littledifference in overall bioavailability of the two preparations.Reconstituted solutions of the palmitate hydrochloride arestable for 2 weeks at room temperature. Such solutionsshould not be refrigerated because thickening occurs thatmakes the preparation difficult to pour.

Clindamycin palmitate hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Clindamycin palmitate hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 195)Lieferanten
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25507-04-4()Verwandte Suche:


  • Clindmycin
  • clindamycin2’-palmitatehydrochloride
  • Methyl7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside2-hexadecanoatemonohydrochloride
  • Clindamycin palmitate hydrochloride
  • Clindamycin Palmitate Hydrochloride (500 mg)
  • Clindamycin Palmitate Hydrochloride (500 mg)G0D334586ug/mg(an)
  • ClindaMycin PalMitate HCl USP
  • methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio- 2-hexadecanoate-L-threo-α-D-galacto-octopyranoside,monohydrochloride
  • Clindamycin Hydrochloride Palmitate
  • Clindamycin 2-Palmitate HCl
  • CLINDAMYCIN PALMITATE HCL
  • Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl] carbonyl]amino]-1-thio-L-threo-α-D-galactooctopyranoside 2-Hexadecanoate Monohydrochloride
  • hexadecanoic acid [6-[2-chloro-1-[[(1-methyl-4-propyl-2-pyrrolidinyl)-oxomethyl]amino]propyl]-4,5-dihydroxy-2-(methylthio)-3-oxanyl] ester
  • Cleocin Pediatric
  • Clindamycin Palmitate Hydrochloride (USP)
  • Clindmycin palmitate hydrochloride USP/EP/BP
  • Clindamycin palmitate hydrochloride USP/EP/BP
  • Clindamycin Palmitate Hydrochloride (1137005)
  • Clindamycin Impurity 85
  • 25507-04-4
  • C34H63CIN2O6SHCL
  • C18H33ClN2O5SHClC18H34Cl2
  • C34H64Cl2N2O6S
  • C34H64Cl2N2O5S
  • Inhibitors
  • PHENYPASTEBAMIN
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