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Imidazolidinyl urea

Imidazolidinyl urea Struktur
39236-46-9
CAS-Nr.
39236-46-9
Englisch Name:
Imidazolidinyl urea
Synonyma:
IMIDAZOLIDINYL UREA;IMIDUREA;Sept 115;germall115;Tristat 1U;Euxyl K 200;Biopure 100;Imidurea NF;Unicide U-13;Imidazolidinyl
CBNumber:
CB3426267
Summenformel:
C11H16N8O8
Molgewicht:
388.29
MOL-Datei:
39236-46-9.mol

Imidazolidinyl urea Eigenschaften

Schmelzpunkt:
141-143℃
Siedepunkt:
514.04°C (rough estimate)
Dichte
1.4245 (rough estimate)
Dampfdruck
0Pa at 25℃
Brechungsindex
1.6910 (estimate)
storage temp. 
2-8°C
L?slichkeit
Soluble in water and in glycerol, but insoluble in almost all organic solvents.
pka
7.41±0.10(Predicted)
Aggregatzustand
Liquid
Farbe
Clear
Wasserl?slichkeit
soluble
Merck 
14,4916
Stabilit?t:
Stable.
InChIKey
ZCTXEAQXZGPWFG-UHFFFAOYSA-N
LogP
0.9 at 20℃
CAS Datenbank
39236-46-9(CAS DataBase Reference)
EPA chemische Informationen
Imidurea (39236-46-9)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36
S-S?tze: 26-36
WGK Germany  2
RTECS-Nr. YT7365000
TSCA  Yes
HS Code  29332990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H317 Kann allergische Hautreaktionen verursachen. Sensibilisierung der Haut Kategorie 1A Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

Imidazolidinyl urea Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36:Reizt die Augen.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

Imidazolidinyl urea is a stable white, free-flowing odorless powder with a mild odour. It does not absorb ultraviolet light, and decomposes at temperatures above 160°C (Sheppard and Wilson, 1974). In aqueous solution the pH is close to neutrality. It is mainly contained in cosmetics and liquid soaps.

Vorbereitung Methode

Imidurea is produced by the condensation of allantoin with formaldehyde.

Definition

ChEBI: Imidazolidinyl urea is a member of ureas. It has a role as an antimicrobial agent. It is an antimicrobial preservative used in cosmetics. It acts as a formaldehyde releaser.

Allgemeine Beschreibung

Imidazolidinyl Urea is a non-aromatic, polar, hydrophilic antimicrobial compound. It is used as a preservative in a variety of applications, most notably in personal care products and cosmetics. It is effective against a broad spectrum of bacteria, fungi and yeast. It is used as a preservative in cosmetics, shampoos, deodorants, body lotions, and in some therapeutic topical ointments and creams.

Pharmazeutische Anwendungen

N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea is a broad-spectrum antimicrobial preservative used in cosmetics and topical pharmaceutical formulations; typical concentrations used are 0.03–0.5% w/w. It is effective between pH 3–9 and is reported to have synergistic effects when used with parabens.

Kontakt-Allergie

Imidazolidinyl urea, a formaldehyde releaser related to diazolidinyl urea (see above), is used as an antimicrobial agent very active against Gram-positive and Gram-negative bacteria, used as a synergist in combination with para- bens. It is used as a preservative in aqueous products, mainly in cosmetics, toiletries, and liquid soaps.

Sicherheit(Safety)

Imidurea is widely used in cosmetics and topical pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material. However, there have been some reports of contact dermatitis associated with imidurea, although these are relatively few considering its widespread use in cosmetics. Although imidurea releases formaldehyde, it does not appear to be associated with cross-sensitization with formaldehyde or other formaldehyde-releasing compounds.
LD50 (mouse, oral): 7.2 g/kg
LD50 (rabbit, skin): > 8 g/kg
LD50 (rat, oral): 11.3 g/kg

Lager

Imidurea is hygroscopic and should be stored in a well-closed container in a cool, dry place.

Inkompatibilit?ten

N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea is incompatible with strong oxidants. It is compatible with other preservatives including sorbic acid and quaternary ammonium compounds. It is also compatible with other pharmaceutical and cosmetic excipients including proteins, nonionic surfactants, and lecithin.

Regulatory Status

Included in the FDA Inactive Ingredients Database (topical preparations). Accepted for use in cosmetics in Europe and the USA. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Imidazolidinyl urea Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Imidazolidinyl urea Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 372)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Wuhan Boyuan Import & Export Co., LTD
+8615175982296
Mike@whby-chem.com China 33 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8807 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12834 58
Nanjing Deda New Material Technology Co., Ltd
+8613223293093
bella@njdeda.com China 80 58
Hebei Yime New Material Technology Co., Ltd.
+86-66697723 +86-17703311139
admin@china-yime.com China 563 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5889 58
Hebei Kingfiner Technology Development Co.Ltd
+86-15532196582 +86-15373005021
lisa@kingfinertech.com China 3009 58
Hangzhou ICH Biofarm Co., Ltd
+86-0571-28186870; +undefined8613073685410
sales@ichemie.com China 1001 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651
admin@zlchemi.com China 3002 58
Hebei Mojin Biotechnology Co.,Ltd
+86-15028179902
angelia@hbmojin.com China 1176 58

39236-46-9()Verwandte Suche:


  • LABOTEST-BB LT00772046
  • 1,1-METHYLENEBIS[3-[3-(HYDROXYMETHYL)-2,5-DIOXO-4-IMIDAZOLIDINYL]UREA]
  • N,N''-METHYLENEBIS[N'-[3-(HYDROXYMETHYL)-2,5-DIOXO-4-IMIDAZOLIDINYL]UREA]
  • N,N''-METHYLENEBIS[N-[3-(HYDROXYMETHYL)-2,5-DIOXO-4-IMIDAZOLIDINYL]UREA]
  • germall115
  • Imidurea (200 mg)
  • IMidazilydinyl urea (IMU)
  • N,N'-Methylenebis[N'-(3-hydroxymethyl-2,5-dioxo-4-imidazolidinyl)urea] Imidurea
  • 1,1'-Methylenebis(3-(3-(hydroxyMethyl)-2,5-dioxoiMidazolidin-4-yl)urea)
  • Imidazolidnyl UREA
  • n,n-methylenebis n'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea
  • methanebis(n,n’-(5-ureido-2,4-diketotetrahydroimidazole)-n,n-dimethylol)
  • n,n’’-methylenebis(n’-(1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-ure
  • n,n’’-methylenebis[n’-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-ure
  • Sept 115
  • Tristat 1U
  • Unicide U-13
  • N,N''-methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]urea]
  • N.N''-Methylenebis-{N'-(3-hydroxymethyl)-2,5-dioxo-4-imidazolenyl-urea}
  • Euxyl K 200
  • Urea, N,N''-methylenebis(N'-(1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)
  • Imidazolidiny Urea
  • Biopure 100
  • Imidurea NF
  • Imidurea, 26-28% nitrogen
  • Urea, N,N-methylenebisN-3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl-
  • ,N'-Methylenebis[N'-(3-Hydroxymethyl-2,5-Dioxo-4-Imidazolidinyl)] Urea
  • 1-imidazolidinylurea
  • Imidazolidinyl urea@100 μg/mL in MeOH
  • N,N'-Methylenebis[N'-3-(hydroxymethyl)-2,5-dioxo-4-imidazoli...
  • 1-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-3-[[[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]carbamoylamino]methyl]urea
  • IMIDAZOLIDINYL UREA(JM 115)
  • IMIDAZOLIDINYL UREA
  • IMIDUREA
  • Abiraterone acetate 154229-18-2
  • N,N'-Methylenebis[N'-3-(hydroxymethyl)-2,5-dioxo-4-
  • 1,1'-Methylenebis(3-(3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)urea)
  • N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea
  • Imidazolidinyl
  • N,N'-Methylenebis[N'-3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl] urea
  • 39236-46-9
  • 39326-46-9
  • 478491-02-8
  • C11H16N8H2O
  • C11H16N8O8
  • Imidazolines/Imidazolidines
  • Heterocyclic Building Blocks
  • Building Blocks
  • Cosmetics
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