ML298 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
ML-298 is an inhibitor of phospholipase D
2 (PLD
2; IC
50 = 355 nM). It is selective for PLD
2 over PLD
1 (IC
50 = 20,000 nM). It decreases invasive migration of U87-MG glioblastoma cells when used at a concentration of 10 μM without inducing cytotoxicity.
Verwenden
ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2).
Biochem/physiol Actions
ML298 is a potent, specific inhibitor of Phospholipase D2 (PLD2; IC50 = 355 nM). ML298 does not affect PLD1 activity at concentrations up to 20 μM.
ML298 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte