(R)-(+)-Methyl p-tolyl sulfoxide
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- CAS-Nr.
- 1519-39-7
- Englisch Name:
- (R)-(+)-Methyl p-tolyl sulfoxide
- Synonyma:
- (R)-(+)-METHYL P-TOLYL SULFOXIDE;(R)-methyl4-methylphenylsulfoxide;1-Methanesulfinyl-4-methyl-benzene;(R)-(+)-Methyl p-tolyl sulfoxide 99%;(R)-1-Methyl-4-(Methylsulfinyl)benzene;1-methyl-4-[(R)-methylsulfinyl]benzene;Benzene, 1-methyl-4-[(R)-methylsulfinyl]-
- CBNumber:
- CB3276835
- Summenformel:
- C8H10OS
- Molgewicht:
- 154.23
- MOL-Datei:
- 1519-39-7.mol
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(R)-(+)-Methyl p-tolyl sulfoxide Eigenschaften
- Schmelzpunkt:
- 73-75 °C(lit.)
- alpha
- 145 º (c=2, acetone)
- Siedepunkt:
- 247.62°C (rough estimate)
- Dichte
- 1.1125 (rough estimate)
- Brechungsindex
- 1.5780 (estimate)
- Aggregatzustand
- Solid
- Optische Aktivit?t
- [α]20/D +145°, c = 2 in acetone
- BRN
- 2040677
(R)-(+)-Methyl p-tolyl sulfoxide Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Verwenden
Used in asymmetric synthesis; adds diastereoselectively to carbony compounds, esters, imines, nitrones, and nitrile oxides.
Allgemeine Beschreibung
(
R)-(+)-Methyl
p-tolyl sulfoxide may be used to prepare (
R)-(+)-methyl 3,5-dimethoxy-6-[8-oxo-9-(
p-tolylsulfinyl) nonyl] benzoate, an intermediate for (
R)-lasiodiplodin synthesis. Its anions undergo addition reaction with nitrones to form optically active a-substituted
N-hydroxylamines. (
R)-(+)-Methyl
p-tolyl sulfoxide also reacts with
O-mesitylsulfonylhydroxylamine (MSH) to form (-)-(
R)-
S-methyl-
S-
p-tolylsulfoximine.
Synthese
(R)-(+)-Methyl p-tolyl sulfoxide is prepared by the nucleophilic displacement of (-)- (1R,2S,5R)-Menthyl (S)-p-Toluenesulfinate with methyl Grignard with complete inversion of configuration at sulfur (eq 1).
(R)-(+)-Methyl p-tolyl sulfoxide Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(R)-(+)-Methyl p-tolyl sulfoxide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 40)Lieferanten
1519-39-7()Verwandte Suche:
- (R)-(+)-METHYL P-TOLYL SULFOXIDE
- (R)-methyl4-methylphenylsulfoxide
- 1-Methanesulfinyl-4-methyl-benzene
- (R)-1-Methyl-4-(Methylsulfinyl)benzene
- (R)-(+)-Methyl p-tolyl sulfoxide 99%
- Benzene, 1-methyl-4-[(R)-methylsulfinyl]-
- 1-methyl-4-[(R)-methylsulfinyl]benzene
- 1519-39-7
- Chiral Building Blocks
- Asymmetric Synthesis
- Organic Building Blocks
- Sulfoxides
- Chiral Compound
- Chiral Building Blocks
- Organic Building Blocks
- Sulfoxides
