PI3-Kinase α Inhibitor 2 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
PI3-Kinase α (PI3Kα) inhibitor 2 is an inhibitor of PI3K p110α (IC
50 = 2 nM in an enzyme assay). It is selective for p110α over p110β, p110γ, and PI3K C2β (IC
50s = 16, 660, and 220 nM, respectively). It also inhibits mammalian target of rapamycin (mTOR; IC
50 = 49 nM). PI3Kα inhibitor 2 inhibits proliferation in A375 melanoma cells with an IC
50 value of 0.58 μM.
PI3-Kinase α Inhibitor 2 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte