Tolbutamide-d9 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Tolbutamide-d₉ is intended for use as an internal standard for the quantification of tolbutamide by GC- or LC-MS. Tolbutamide is an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel K_ir6.2 (IC₅₀ = 4.9 μM). It is selective for SUR1/K_ir6.2 over SUR2A/K_ir6.2 and SUR2B/K_ir6.2 channels (IC₅₀s = 85 and 88 μM, respectively). Tolbutamide increases glucose-induced insulin secretion and calcium influx in isolated mouse pancreatic islets. In vivo, tolbutamide (80 mg/kg) reduces blood glucose levels in a mouse model of diabetes induced by streptozotocin (STZ; ). Formulations containing tolbutamide have been used in the treatment of type 2 diabetes.

Chemische Eigenschaften

White Solid

Verwenden

Labelled Tolbutamide (T535150). An antidiabetic, used as a hypoglycemic agent in veterinary medicine.

Tolbutamide-d9 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Tolbutamide-d9 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32321	50
Alta Scientific Co., Ltd.	022-6537-8550 15522853686	sales@altasci.com.cn	China	4511	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Nanjing Haolv Biotechnology Co.,Ltd	025-84622273 17361806303	3004208264@qq.com	China	3021	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 +86-13028896684;	sales@rrkchem.com	China	57423	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44806	58
ChengDu SinoStandards Bio-Tech Co.,Ltd. ，	028-83243028 19136088901	sinostandards@163.com	China	4985	58
Yancheng Tongming Biotechnology Co., Ltd.	15195160625	2863565288@qq.com	China	5192	58

1219794-57-6()Verwandte Suche:

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• 1-(Butyl-3-(p-tolyl- sulfonyl)urea-d9
• 3-(p-Tolyl-4-sulfonyl)-1-butylurea-d9
• Artosin-d9
• Artozin-d9
• Mobenol-d9
• N-[(ButylaMino-d9)carbonyl]-4-MethylbenzenesulfonaMide
• N-Butyl-N'-(4-Methylphenylsulfonyl)urea-d9
• Tolylsulfonylbutylurea-d9
• 1-(4-methylphenyl)sulfonyl-3-(1,1,2,2,3,3,4,4,4-nonadeuteriobutyl)urea
• Tolbutamide-d9 Solution, 100ppm
• [2H9]-Tolbutamide
• N-[(butyl-1,1,2,2,3,3,4,4,4-d9-amino)carbonyl]-4-methyl-benzenesulfonamide
• 1219794-57-6
• C12H9D9N2O3S
• Aromatics
• Intermediates & Fine Chemicals
• Isotope Labelled Compounds
• Pharmaceuticals
• Sulfur & Selenium Compounds