2'-Desoxyguanosin
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2'-Desoxyguanosin Eigenschaften
- Schmelzpunkt:
- 300 °C
- Siedepunkt:
- 410.43°C (rough estimate)
- Dichte
- 1.3382 (rough estimate)
- Brechungsindex
- -42 ° (C=0.2, 1mol/L NaOH)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- L?slichkeit
- NH4OH 1 M: 50 mg/mL, clear to very faintly turbid, yellow to brown
- Aggregatzustand
- powder
- pka
- 9?+-.0.20(Predicted)
- Farbe
- White to Off-white
- PH
- 2.37;9.33
- Wasserl?slichkeit
- Slightly soluble in water.
- maximale Wellenl?nge (λmax)
- 255 (pH 1)
- BRN
- 39814
- InChIKey
- OROIAVZITJBGSM-OJFKHTATSA-N
- CAS Datenbank
- 961-07-9(CAS DataBase Reference)
- NIST chemische Informationen
- Deoxyguanosine(961-07-9)
- EPA chemische Informationen
- Guanosine, 2'-deoxy- (961-07-9)
Sicherheit
R-S?tze: | 20/21/22 | ||
---|---|---|---|
S-S?tze: | 24/25 | ||
WGK Germany | 3 | ||
RTECS-Nr. | MF8760000 | ||
F | 10-23 | ||
TSCA | Yes | ||
HS Code | 29349990 |
2'-Desoxyguanosin Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.Chemische Eigenschaften
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents.Verwenden
2'-Deoxyguanosine (Deoxyguanosine; dG) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. It is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.Definition
ChEBI: 2'-deoxyguanosine is a purine 2'-deoxyribonucleoside having guanine as the nucleobase. It has a role as a Saccharomyces cerevisiae metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purines 2'-deoxy-D-ribonucleoside and a purine 2'-deoxyribonucleoside. It is functionally related to a guanosine.Biologische Funktion
2‘-Deoxyguanosine (2’dGuo) is a purine nucleoside metabolite that has been shown to inhibit proliferation-dependent antigen-specific suppressor T cell (Ts) function in mouse and human systems. 2'dGuo also inhibits mitogen-induced T cell proliferation. Low concentrations (40 gM) of 2'dGuo enhanced phytohemagglutinin- and amantadine A-induced T-cell transformation, possibly due to the inhibition of T-cell function leading to the promotion of T-cell growth factor production. T-cell responses were inhibited only when the concentration of 2'dGuo was toxic to lymphocytes.[1]l?uterung methode
2'-Deoxyguanosine recrystallises from H2O as the monohydrate. [Brown &C5440 Lythgoe J Chem Soc 1990 1950, L2'-Desoxyguanosin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2'-Desoxyguanosin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 481)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Wuhu Nuowei chemistry Co., Ltd. | +86-0553-2911116-802 +86-18055311600 |
sales1@nuowei-chem.com | China | 1638 | 58 |
Beijing Ribio Biotech Co.,Ltd | 010-62664360 +8613328773880 |
wucy@ribio.com.cn | China | 117 | 58 |
Nanjing Duly Biotech Co.,Ltd | +undefined18013301590 |
doris@njduly.com | China | 2450 | 58 |
Hangzhou Measure Life Technology Co., LTD | +8613343730176 |
2924244016@qq.com | China | 83 | 58 |
Hangzhou Weitai Biological Pharmaceutical Co.,Ltd. | +86-86-057182358004 +8613588879771 |
info@weitai-pharmaceutical.com | China | 61 | 58 |
Hebei Chuanghai Biotechnology Co., Ltd | +86-15531157085; +8615531157085 |
abby@chuanghaibio.com | China | 8807 | 58 |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12789 | 58 |
HangZhou RunYan Pharma Technology Co.,LTD. | +8618882027439 |
sales2@runyanpharma.com | China | 302 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21628 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29856 | 58 |
961-07-9(2'-Desoxyguanosin)Verwandte Suche:
3-α,12-α-Dihydroxy-5-β-cholan-24-sure
Melibiose
2-Amino-9-beta-D-ribofuranosyl-9H-purine-6-(1H)-one hydrate
Guanin
Aciclovir
Chloralhydrat
5'-Guanylsure
Guanosin-5'-(dinatriumphosphat)
DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS*
5'-O-[Bis(4-methoxyphenyl)benzyl]-2'-desoxy-N-(2-methyl-1-oxopropyl)guanosin
2'-Desoxyguanosin-5'-(tetrahydrogentriphosphat)
2'-Desoxy-5'-guanylsure
Guanylic acid sodium salt
hydrazine hydrate
hydrate
2'-Desoxyguanosin
Deoxynucleotide
Deoxidizer
- DEOXYGUANOSINE-2'
- GUANINE DESOXYRIBOSIDE
- 2'-DEOXY-D-GUANOSINE
- A-2'-DEOXYGUANOSINE
- 9-(2'-DEOXY-BETA-D-RIBOFURANOSYL)GUANINE
- 2(acute)-Deoxyguanosine
- 2-amino-9-(4-hydroxy-5-methylol-tetrahydrofuran-2-yl)-3H-purin-6-one
- 2-amino-9-[4-hydroxy-5-(hydroxymethyl)-2-tetrahydrofuranyl]-3H-purin-6-one
- 2-amino-9-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one
- 9H-Purin-6-ol, 2-amino-9-(2-deoxy-9-beta-D-ribofuranosyl)-
- deoxyephedrinearenol2’-deoxyguanosine
- Desoxyguanosine
- Guanine deoxy nucleoside
- Guanine deoxyriboside
- Guanine, 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-
- 2-DEOXYGUANOSINE extrapure
- 9-(2-Deoxy-β-D-ribofuranosyl)guanine, Guanine-2μ-deoxyriboside
- Norway saltpeter-15N2
- 2'-Deoxyguanosine ,98%
- 2'-Deoxyguanosine mo
- 2'-DEOXYGUANOSINE:H2O
- 2’-deoxy-guanosin
- Deoxyguanosine Monohydrat
- 2-aMino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one hydrate
- 2'-Deoxyguanosine Monohydrate SynonyMs 9-(2-Deoxy-beta-D-ribofuranosyl)guanine hydrate
- 2-AMino-9-((2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-3H-purin-6(9H)-one
- 2'-Deoxyguanosine Hydrate, 98.0%(T)
- 9-(2-Deoxy-β-D-ribofuranosyl)guanine
- 2'-DEOXYGUANOSINE CELL CULTURE TESTED
- DeoxyguanosineMonohydrate,Isolated
- 2'-Deoxyguanosine hydrate, 99+%
- 9-(2-deoxy-á-d-ribofuranosyl)guanine hydrate
- guanine-2'-deoxyriboside hydrate
- 2-amino-9-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
- guaninedeoxyriboside
- Guanosine, 2'-deoxy-
- NSC 22837
- 9-(2-Deoxy-beta-D-ribofuranosyl)guanine hydrate
- Guanine-2'-deoxyriboside monohydrate
- 2-amino-9-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
- 9-(2-Deoxy--D-erythro-pentofuranosyl)guanine Monohydrate
- Deoxyguanosine Monohydrate
- Guanine Deoxyriboside Monohydrate
- 2'-Deoxyguanosine monohydrate (dG)
- D8415_SIGMA
- Guanine, 9-(
- NCGC00096112-01
- Oprea1_013861
- Oprea1_263480
- CHEMILUMINESCENT WESTERN BLOT KIT,ANTI R
- CHEMILUMINESCENT WESTERN BLOT KIT,ANTI M
- O6-Methyl-2&rsquo
- 2'-Desoxyguanosin
- 7-Methyl-7-deaza-2&rsquo
- N1-Methyl-2&rsquo
- 8-Oxo-N2-isobutyryl-2&rsquo
- 8-(4-Amino-phenyl)-2&rsquo
- 2'-Deoxyguanosine(Dg)