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methyl orsellinate

methyl orsellinate Struktur
3187-58-4
CAS-Nr.
3187-58-4
Englisch Name:
methyl orsellinate
Synonyma:
Methyl;METHYL ORSELLINATE;Methyl o-orsellinate;Orsellinic acid methyl;o-Orsellinic acid methyl;6-Methyl-β-resorcylicacidmethyl;6-Methyl-β-resorcylic acid methyl;BENZOIC ACID,2,4-DIHYDROXY-6-METHYL-, METHYL ESTER
CBNumber:
CB31484897
Summenformel:
C9H10O4
Molgewicht:
182.17
MOL-Datei:
3187-58-4.mol

methyl orsellinate Eigenschaften

Schmelzpunkt:
141-142℃
Siedepunkt:
339℃
Dichte
1.296
Flammpunkt:
138℃
storage temp. 
2-8°C
L?slichkeit
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
8.27±0.23(Predicted)
Farbe
White to Off-White
InChI
InChI=1S/C9H10O4/c1-5-3-6(10)4-7(11)8(5)9(12)13-2/h3-4,10-11H,1-2H3
InChIKey
NCCWCZLEACWJIN-UHFFFAOYSA-N
SMILES
C(OC)(=O)C1=C(C)C=C(O)C=C1O
LogP
2.380 (est)
EPA chemische Informationen
Benzoic acid, 2,4-dihydroxy-6-methyl-, methyl ester (3187-58-4)

Sicherheit

HS Code  2918290090

methyl orsellinate Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Methyl 2,4-Dihydroxy-6-methylbenzoate (methyl orsellinate) is a useful synthetic intermediate in the synthesis of Grifolic Acid (G786500); a selective partial GPR120 agonist. Grifolic Acid induces ERK and [Ca2+]i responses in cells expressing GPR120, but has no effects on those expressing GPR40.

Biochem/physiol Actions

Methyl orsellinate, an antifungal compound, is produced during submerged culture from Sparassis crispa. Methyl orsellinate have appeared to have higher antifungal activity than sparassol. Methyl orsellinate is a phytotoxic compound; it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus and Echinochloa crus-galli, interact with bovine-brain calmodulin and inhibit the activation of the calmodulin-dependent enzyme cAMP phosphodiesterase. It could inhibit PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 microM; the selective inhibition of PTP1B has been widely recognized as a potential drug target for the treatment of type 2 diabetes and obesity; methyl orsellinate may treat the type 2 diabetes and obesity.

methyl orsellinate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


methyl orsellinate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 51)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Zhengzhou Anbu Chem Co.,Ltd
+86-0371-88006763; +8615988602810
sales@anbuchem.com China 2998 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-81138252 +86-18789408387
1057@dideu.com China 3958 58
Xiamen Work-For-World Medicine Co.,Ltd.
+8615921822462
co@wfwmed.com China 403 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63687 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29811 58
Win-Win chemical CO., Limited
+86-0086-577-64498589 +86-15355981851
sales@win-winchemical.com China 14347 58
LEAP CHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 24727 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38469 58
PNP Biotech Co. Ltd
+8618516098983
sales@pnpbiotech.com China 1001 58

3187-58-4()Verwandte Suche:


  • Orsellinic acid methyl
  • 6-Methyl-β-resorcylic acid methyl
  • Methyl o-orsellinate
  • o-Orsellinic acid methyl
  • BENZOIC ACID,2,4-DIHYDROXY-6-METHYL-, METHYL ESTER
  • 6-Methyl-β-resorcylicacidmethyl
  • METHYL ORSELLINATE
  • Methyl
  • 3187-58-4
  • Aromatic Esters
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