ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Adenosine 5′-triphosphate, periodate oxidized sodium salt has been used:

• as an antagonist of the purinergic receptor, P2 × 7 to inhibit P2 × 7 pathway
• as a nonspecific agonist to assess the activity of P2×₇-R by the mobilization of Ca²⁺
• to evaluate the physiological significance of elevated intracellular ATP levels
• increased?P2rx7?expression for osteoclastogenesis in?Flcn-deficient cells

Allgemeine Beschreibung

A 2′,3′-dialdehyde derivative of ATP that is commonly used to affinity label nucleotide sites in enzymes. Acts as a specific, irreversible antagonist of P2Z/P2X₇ purinergic receptors in J774 mouse macrophages. Does not affect P2_γ receptors. Inhibits inflammatory pain in arthritic rat model by blocking ATP action on P2X₇ receptor in nerve terminals. Also shown to irreversibly block ATP-induced Ca²⁺ influx in lymphocytes (?100 μM). O-ATP-treated mice display better preservation and lower rate of rejection of pancreatic islet grafts with reduced Th1 transcripts.

Biochem/physiol Actions

Reversible: no

ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Aladdin Scientific		tp@aladdinsci.com	United States	52924	58
TargetMol Chemicals Inc.	+8613564774135	zijue.cai@tsbiochem.com	United States	19881	58
Tianjin heowns Biochemical Technology Co., Ltd.	400 638 7771	sales@heowns.com	China	14435	57
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24641	58
Shanghai Yingxin laboratory equipment Co., Ltd	021-021-59178156 15300768757	359382369@qq.com	China	10674	58
Shanghai Guchen Biotechnology Co., LTD	021-34675735 19147740836	1986399151@qq.com	China	9844	58
Merck KGaA	(+86) 21 2033 8288	sigmaname@qq.com	CHINA	292394	58

71997-40-5()Verwandte Suche:

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• ADENOSINE 5'-TRIPHOSPHATE, PERIODATE OXIDIZED SODIUM SALT
• ADENOSINE 5'-TRIPHOSPHATE-2', 3'-DIALDEHYDE SODIUM SALT
• oATP
• ADENOSINE 5-TRIPHOSPHATE, PERIODATEOXIDI ZED SODIUM
• adenosine 5'-triphosphate-2',3'-dialdehyde
• Adenosine 5`-triphosphate sodiuM salt periodate oxidized
• Adenosine 5′-triphosphate, periodate oxidized
• Oxidized ATP (oATP) - CAS 71997-40-5 - Calbiochem
• Oxidized ATP trisodium salt
• ADENOSINE 5'-TRIPHOSPHATE PERIODATE OXIDIZED
• Oxidized ATP (oATP)
• 71997-40-5
• C10H14N5O13P3
• C10H13N5NaO13P3
• Nucleotides
• Nucleosides, Nucleotides, Oligonucleotides
• Biochemicals and Reagents
• BioChemical