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Thalicarpine

Thalicarpine Struktur
5373-42-2
CAS-Nr.
5373-42-2
Englisch Name:
Thalicarpine
Synonyma:
Nsc68075;Aids002681;Aids-002681;Thalicarpine;Thaliblastine;(6aS)-9-[4,5-Dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl]methyl]phenoxy]-5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline;4H-Dibenzo[de,G]quinoline, 9-[4,5-dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6as)-;4H-Dibenzo(de,G)quinoline, 9-(4,5-dimethoxy-2-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (S-(R*,R*))-
CBNumber:
CB31179887
Summenformel:
C41H48N2O8
Molgewicht:
696.83
MOL-Datei:
5373-42-2.mol

Thalicarpine Eigenschaften

Schmelzpunkt:
160-161°
alpha 
D25 +133° (c = 0.83 in methanol); D25 +89° (c = 0.88 in chloroform)
Siedepunkt:
701.43°C (rough estimate)
Dichte
1.1544 (rough estimate)
Brechungsindex
1.4670 (estimate)
pka
7.62±0.40(Predicted)

Sicherheit

Thalicarpine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

A complex alkaloid, thaliblastine occurs in Thalictrum minus elatum and has been assigned the structure given on the basis of chemical and spectroscopic investigations. The alkaloid has marked antitumour activity but rapid administration of the base causes brachycardia, hypotension and inhibition of respiration in laboratory animals. Slow intravenous injection, however, produces none of these effects. Thaliblastine is cytotoxic to HEF and Sa9 cells in vitro.

Einzelnachweise

Todorov, Damyanova,Dokl. Bolg. Akad. Nauk., 28, 709 (1975)

Thalicarpine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Thalicarpine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 4)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21634 55
TargetMol Chemicals Inc. 		+8613564774135
 zijue.cai@tsbiochem.com United States 19885 58
TargetMol Chemicals Inc. 15002134094
 marketing@targetmol.cn China 19704 58

5373-42-2()Verwandte Suche:

  • Thalicarpine
  • (6aS)-9-[4,5-Dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl]methyl]phenoxy]-5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinoline
  • Thaliblastine
  • 4H-Dibenzo(de,G)quinoline, 9-(4,5-dimethoxy-2-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (S-(R*,R*))-
  • 4H-Dibenzo[de,G]quinoline, 9-[4,5-dimethoxy-2-[[(1S)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-5,6,6A,7-tetrahydro-1,2,10-trimethoxy-6-methyl-, (6as)-
  • Aids002681
  • Aids-002681
  • Nsc68075
  • 5373-42-2
  • C41H48N2O8
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