MK-677
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- CAS-Nr.
- 159634-47-6
- Englisch Name:
- MK-677
- Synonyma:
- MK-677;Ibutamoren;Mk677 Sarms;IbutaMoren (MK-677);L 163191;MK-0677;MK-677;IBUTAMOREN (MK-677), CID178024;MK-677?/?Ibutamoren 10mg Tablets;Ibutamoren,MK-677, MK-0677, L-163,191;Ibutamoren mesylate (MK-0667, L163191);(R)-2-amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide
- CBNumber:
- CB31178916
- Summenformel:
- C27H36N4O5S
- Molgewicht:
- 528.66
- MOL-Datei:
- 159634-47-6.mol
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MK-677 Eigenschaften
- Dichte
- 1.32
- pka
- 15.73±0.46(Predicted)
- InChIKey
- UMUPQWIGCOZEOY-JOCHJYFZSA-N
- SMILES
- C(N[C@H](COCC1=CC=CC=C1)C(N1CCC2(CC1)C1=C(N(S(C)(=O)=O)C2)C=CC=C1)=O)(=O)C(N)(C)C
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
![GHS hazard pictograms]() src="/GHS06.jpg" width="20" height="20" /> |
P264, P270, P301+P310, P321, P330,P405, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P321 |
Besondere Behandlung |
| P330 |
Mund ausspülen. |
| P405 |
Unter Verschluss aufbewahren. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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MK-677 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Ibutamoren (INN) (developmental code names MK-677, MK-0677, L-163,191)is a non-peptidic, potent, long acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin.
It has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels. MK677 has shown to sustain activation of GH-IGF-1 Axis and increase in lean body mass but no change in total fat mass or visceral fat.
It is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency, and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly.
Verwenden
Growth
hormone releasing factor.
benefits
The benefits of MK-677 include muscle-building, a reduction in muscle wasting, better bone density, improved sleep, and anti-aging properties. It may also have nootropic effects and it can be beneficial in treating growth hormone deficiencies.
Sicherheit(Safety)
Ibutamoren is a muscle building anabolic compound. It's considered safe if you don't have high blood glucose level and if you don't suffer from congestive heart failure. It's considered a boon for anti aging and it's a life longevity material. It's considered to be more beneficial than to be harmful. The optimal dose for body building is to take 25mg at bedtime for four to six weeks. It is a water retaining compound so beware of bloating.
MK-677 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Spiro[3H-indole-3,4'-piperidine], 1'-[(2R)-2-amino-1-oxo-3-(phenylmethoxy)propyl]-1,2-dihydro-1-(methylsulfonyl)-
Spiro[3H-indole-3,4'-piperidine]-1'-carboxylic acid, 1,2-dihydro-1-(methylsulfonyl)-, phenylmethyl ester
(R)-tert-butyl (3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)carbamate
Benzyl 4-(chlorocarbonyl)tetrahydro-1(2H)-pyridinecarboxylate
1-(methylsulfonyl)spiro[indoline-3,4'-piperidine]
MK677
benzyl spiro[indole-3,4'-piperidine]-1'-carboxylate
1'-(BENZYLOXYCARBONYL)SPIRO(INDOLINE-3,4'-PIPERIDINE)
4-FORMYL-N-CBZ-PIPERIDINE
1-[(Benzyloxy)carbonyl]piperidine-4-carboxylic acid
Boc-D-Ser(Bzl)-OH
4-Piperidincarbonsure
Phenylhydrazin
α-Bromtoluol
Downstream Produkte
MK-677 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 57)Lieferanten
- 2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide
- IbutaMoren (MK-677)
- Ibutamoren
- 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide
- IBUTAMOREN (MK-677), CID178024
- Ibutamoren,MK-677, MK-0677, L-163,191
- L 163191;MK-0677;MK-677
- (R)-2-amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide
- Ibutamoren mesylate (MK-0667, L163191)
- Propanamide, 2-amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methyl-
- Mk677 Sarms
- 159634-47-6 (R)-2-amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide
- MK-677
- MK-677?/?Ibutamoren 10mg Tablets
- (R)-2-amino-N-(3-(benzyloxy)-1-(1-(methylsulfonyl)spiro[indoline-3,4'-piperidin]-1'-yl)-1-oxopropan-2-yl)-2-methylpropanamide
- 159634-47-6
- C27H36N4O5S
