Fosmidomycin
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Fosmidomycin Eigenschaften
- Schmelzpunkt:
- 158-160° (dec); mp 160-166° (dec) (Hemmi)
- storage temp.
- -20°C
- L?slichkeit
- H2O: soluble20mg/mL, clear
- Aggregatzustand
- powder
- Farbe
- white to beige
- Wasserl?slichkeit
- H2O: 20mg/mL, clear
Sicherheit
WGK Germany | 3 | ||
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Toxizit?t | LD50 in mice and rats (mg/kg): >11000 orally; ~8000 s.c. (Wiesner, 2003) |
Fosmidomycin Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Fosmidomycin sodium salt hydrate has been used as an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a study to determine monotropin carvacrol biosynthesis in Satureja khuzistanica plant.Definition
ChEBI: Propylphosphonic acid in which one of the hydrogens at position 3 is substituted by a formyl(hydroxy)amino group. An antibiotic obtained from Streptomyces lavendulae, it specifically inhibits DXP reductoisomerase (EC 1.1.1.267), a key enzyme i the non-mevalonate pathway of isoprenoid biosynthesis.Biochem/physiol Actions
Fosmidomycin is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) (MEP synthase): an antimalarial compound. 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway).Fosmidomycin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Fosmidomycin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 5)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
BOC Sciences | 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 14055 | 65 |
Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 |
isunpharm@qq.com | China | 4674 | 55 |
Suzhou Vosun Biotech Co.,Ltd | 0512-66569378-8002 66569378 |
info@vosunchemical.com | China | 725 | 58 |
Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 |
czbjpharma@126.com | China | 18478 | 58 |
- 3-(Formylhydroxyamino)propylphosphonic acid
- 3-Phosphono 1-(N-formylhydroxyamino)propane
- Antibiotic FR-31705
- 10 Mg, 50 Mg, 100 Mg, 1g
- (3-(N-hydroxyforMaMido)propyl)phosphonic acid
- (3-(N-Hydroxyformamido)propyl)phosphonic acid sodium salt
- Fosmidomycin sodium salt hydrate
- Phosphonic acid, P-[3-(formylhydroxyamino)propyl]-
- 66508-53-0