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HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS

HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Struktur
29400-42-8
CAS-Nr.
29400-42-8
Englisch Name:
HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS
Synonyma:
fumigacin;Helvolic acid (Fumigacin);HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS;6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-beta)--alph;17(20),24-trien-21-oicacid,6,16-bis(acetyloxy)-3,7-dioxo-29-nordammara-(4;(8α,9β,13α,14β,17Z)-6β,16β-Diacetoxy-3,7-dioxo-29-nor-5α-dammara-1,17(20),24-trien-21-oic acid;(8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid;(4α,8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid;29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4α,6β,8α,9β,13α,14β,16β,17Z)-
CBNumber:
CB2503570
Summenformel:
C33H44O8
Molgewicht:
568.7
MOL-Datei:
29400-42-8.mol

HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Eigenschaften

Schmelzpunkt:
215°
alpha 
D25 -121° (chloroform)
Siedepunkt:
552.56°C (rough estimate)
Dichte
1.1062 (rough estimate)
Brechungsindex
1.4900 (estimate)
storage temp. 
2-8°C
L?slichkeit
DMF:30.0(Max Conc. mg/mL);52.75(Max Conc. mM)
DMSO:20.0(Max Conc. mg/mL);35.17(Max Conc. mM)
Ethanol:20.0(Max Conc. mg/mL);35.17(Max Conc. mM)
Aggregatzustand
A crystalline solid
pka
4.05±0.41(Predicted)
Farbe
White to off-white

Sicherheit

RTECS-Nr. RC1370000
HS Code  29419000

HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Helvolic acid is a mycotoxin originally isolated from A. fumigatus that has broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria. At 4-16 mg/L, it acted synergistically with erythromycin (500-2,000 mg/L) in vitro on five multi-drug resistant strains of S. aureus. At 10 mg/kg/d, it reduced tumor growth and prolonged survival synergistically with cyclophosphamide (20 mg/kg/d) in a mouse model of sarcoma but had no effect when administered alone.

Verwenden

Helvolic acid is a mycotoxin with antibacterial activity.

Definition

ChEBI: A steroid C-21 acid having a 29-nordammarane skeleton substituted with an acetoxy group at C-16 and oxo groups at C-3 and -7, with double bonds at C-1, -17(20) and -24.

HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 27)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32956 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
BOC Sciences 		16314854226; +16314854226
 inquiry@bocsci.com United States 19741 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
 lucy@atkchemical.com China 9952 58
Lynnchem 86-(0)29-85992781 17792393971
 info@lynnchem.com China 4587 58
Novachemistry 44-20819178-90 02081917890
 info@novachemistry.com United Kingdom 4381 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58

29400-42-8()Verwandte Suche:

  • 17(20),24-trien-21-oicacid,6,16-bis(acetyloxy)-3,7-dioxo-29-nordammara-(4
  • 6-beta,8-alpha,9-beta,13-alpha,14-beta,16-beta,17-beta)--alph
  • fumigacin
  • HELVOLIC ACID FROM CEPHALOSPORIUM*CAERULENS
  • (4α,8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid
  • (8α,9β,13α,14β,17Z)-6β,16β-Bis(acetyloxy)-3,7-dioxo-29-nordammara-1,17(20),24-trien-21-oic acid
  • (8α,9β,13α,14β,17Z)-6β,16β-Diacetoxy-3,7-dioxo-29-nor-5α-dammara-1,17(20),24-trien-21-oic acid
  • 29-Nordammara-1,17(20),24-trien-21-oic acid, 6,16-bis(acetyloxy)-3,7-dioxo-, (4α,6β,8α,9β,13α,14β,16β,17Z)-
  • Helvolic acid (Fumigacin)
  • 29400-42-8
  • C33H44O8
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