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Dolutegravir O-β-D-Glucuronide Impurity

Dolutegravir O-β-D-Glucuronide Impurity Struktur
1485692-21-4
CAS-Nr.
1485692-21-4
Englisch Name:
Dolutegravir O-β-D-Glucuronide Impurity
Synonyma:
-D-Glucuronide;M3 Of dolutegravir;Dolutegravir O-β-D-Glucuronide;Dolutegravir O-β-D-Glucuronide;Dolutegravir O-β-D-Glucuronide Impurity;β-D-Glucopyranosiduronic acid, (4R,12aS)-9-[[[(2,4-difluorophenyl)methyl]amino]carbonyl]-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazin-7-yl
CBNumber:
CB24796147
Summenformel:
C26H27F2N3O11
Molgewicht:
595.51
MOL-Datei:
1485692-21-4.mol

Dolutegravir O-β-D-Glucuronide Impurity Eigenschaften

Schmelzpunkt:
122 - 124°C
Siedepunkt:
934.5±65.0 °C(Predicted)
Dichte
1.67±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
L?slichkeit
Methanol (Very Slightly), Water (Slightly, Sonicated)
Aggregatzustand
Solid
pka
2.76±0.70(Predicted)
Farbe
White to Pale Yellow
Wasserl?slichkeit
Water: slightly, sonicated

Sicherheit

Dolutegravir O-β-D-Glucuronide Impurity Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Dolutegravir O-β-D-Glucuronide is a metabolite of Dolutegravir (D528800); a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir O-β-D-Glucuronide Impurity Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Dolutegravir O-β-D-Glucuronide Impurity Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 8)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Shenzhen Regent Biochemical Technology Co., Ltd. 0755-0755-85201366 18938635012
 sales@regentsciences.com China 9371 58
Energy Chemical 021-58432009 400-005-6266
 marketing1@energy-chemical.com China 44806 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24644 58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd 18502726233; 18502726233
 3641133981@qq.com China 9711 58
  • Dolutegravir O-β-D-Glucuronide Impurity
  • Dolutegravir O-β-D-Glucuronide
  • -D-Glucuronide
  • Dolutegravir O-β-D-Glucuronide
  • β-D-Glucopyranosiduronic acid, (4R,12aS)-9-[[[(2,4-difluorophenyl)methyl]amino]carbonyl]-3,4,6,8,12,12a-hexahydro-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazin-7-yl
  • M3 Of dolutegravir
  • 1485692-21-4
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