PACFA-18:1 PC Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
The pacFA lipid attached to 2-oleoyl-
sn-glycero-3-phosphocholine, contains a photoactivable diazirine ring with a clickable alkyne group.
Biochem/physiol Actions
1-(9-(3-pent-4-ynyl-3-H-diazirin-3-yl)-nonanoyl)-2-oleoyl-sn-glycero-3-phosphocholine (pacFA-18:1 PC) may be used for global analysis of protein–lipid interactions in living cells. pacFA acts as a precursor for the biosynthesis of bifunctional lipids. Proteins in contact with the bifunctional lipids are then cross-linked by ultraviolet (UV) irradiation of the diazirine ring. Finally, click chemistry is used to label the alkyne with a reporter molecule.
PACFA-18:1 PC Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
