Febuprol
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- CAS-Nr.
- 3102-00-9
- Bezeichnung:
- Febuprol
- Englisch Name:
- Febuprol
- Synonyma:
- h-33;valbil;k-10033;FEBUPROL;Valbilan;NSC 30151;Febuprol USP/EP/BP;1-butoxy-3-phenoxy-2-propano;1-butoxy-3-phenoxy-2-propanol;2-Propanol, 1-butoxy-3-phenoxy-
- CBNumber:
- CB2400277
- Summenformel:
- C13H20O3
- Molgewicht:
- 224.3
- MOL-Datei:
- 3102-00-9.mol
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Febuprol Eigenschaften
- Schmelzpunkt:
- 25°C
- Siedepunkt:
- bp11 165°; bp1.0 125-132°
- Dichte
- d420 1.027
- Brechungsindex
- nD20 1.5004
- storage temp.
- 2-8°C
- CAS Datenbank
- 3102-00-9(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Toxizit?t |
LD50 in mice, rats (mg/kg): 3050, 2370 orally; 436, 400 i.p. (Hofrichter) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Febuprol Chemische Eigenschaften,Einsatz,Produktion Methoden
Originator
Valbil,Rohm Pharma,W. Germany,1981
Manufacturing Process
Initially, 4.5 g (0.08 mol) pulverized potassium hydroxide was dissolved in
300 ml isopropanol in a 500 ml four-neck flask equipped with stirrer, intensive
cooler, dropping funnel and feed pipe for the gas treatment with nitrogen.
Then, 52.0 g (0.4 mol) n-butylglycidyl ether and 41.4 g (0.44 mol) phenol
was added thereto, whereafter the material was heated to boiling under
nitrogen. The material was stirred, about 8.5 hours, until no glycidyl ether
could be determined, e.g., by gas chromatography.
After the suspension was cooled under nitrogen, the solvent was distilled off
under vacuum. The residue was taken up in 200 ml water and the milky
emulsion extracted exhaustively with ether. From the organic phase, the
excess butylglycidyl ether was extracted with diluted potassium hydroxide
solution. The ether phase was washed neutral with water and the solvent
removed after drying with sodium sulfate. The remaining oily residue was
distilled under vacuum; there was obtained a colorless liquid of BP
123.5°C/0.07 mm. Yield: 81.8 g (91.1% of the theory)
Therapeutic Function
Choleretic
Febuprol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Febuprol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 37)Lieferanten
3102-00-9(Febuprol)Verwandte Suche:
- (3-n-butoxy-2-hydroxypropyl)phenylether
- 1-butoxy-3-phenoxy-2-propano
- 1-butoxy-3-phenoxy-2-propanol
- 3-n-butoxy-1-phenoxy-2-propanol
- h-33
- k-10033
- 1-butoxy-3-(phenoxy)propan-2-ol
- FEBUPROL
- valbil
- 2-Propanol, 1-butoxy-3-phenoxy-
- Febuprol USP/EP/BP
- NSC 30151
- Valbilan
- 3102-00-9
- C13H20O3
- API
