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(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Struktur
1417997-93-3
CAS-Nr.
1417997-93-3
Englisch Name:
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
Synonyma:
22d;HDAC8-IN-1;CS-2693;MDK-7933;INVIVO-7933;HDAC8-IN-22d;HDAC8-IN-1(22d);HDAC8 inhibitor 1;HDAC8 inhibitor 22d;HDAC8-IN-1 ,MDK7933
CBNumber:
CB23373154
Summenformel:
C22H19NO3
Molgewicht:
345.39
MOL-Datei:
1417997-93-3.mol

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Eigenschaften

Dichte
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO: soluble
Aggregatzustand
A solid
pka
8.76±0.23(Predicted)
Farbe
White to off-white

Sicherheit

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

HDAC8-IN-1 is an inhibitor of histone deacetylase 8 (HDAC8; IC50 = 27.2 nM). It is selective for HDAC8 over HDAC1-3, -4, -6, -10, and -11 (IC50s = ≥3,000 nM for all). HDAC8-IN-1 is cytotoxic to A549, H1299, and CL1-5 lung cancer cells (IC50s = 7.9, 7.2, and 7 μM, respectively).

Verwenden

(2E)-N-Hydroxy-3-(5-methoxy[1,1'':4'',1''''-terphenyl]-2-yl)-2-propenamide, is a HDAC8 inhibitor with an IC50 of 27.2 nM.

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

2-Propenoic acid, 3-(2-hydroxy-4-methoxyphenyl)-, ethyl ester, (E)- 7-Methoxycumarin

Downstream Produkte

(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 68)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32956 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30238 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10473 58
Henan Alfa Chemical Co., Ltd
China 11415 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652
 info@fdachem.com China 20283 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
  • INVIVO-7933
  • (E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide
  • (2E)-N-Hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-2-propenamide
  • 2-Propenamide, N-hydroxy-3-(5-methoxy[1,1':4',1''-terphenyl]-2-yl)-, (2E)-
  • HDAC8-IN-22d
  • HDAC8 inhibitor 22d
  • CS-2693
  • HDAC8 inhibitor 1
  • MDK-7933
  • HDAC8-IN-1 ,MDK7933
  • (E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
  • 22d
  • HDAC8-IN-1
  • HDAC-8-IN-1,HDAC8IN1,Histone deacetylases,Inhibitor,inhibit,HDAC,HDAC8 IN 1
  • HDAC8-IN-1(22d)
  • (E)-N-Hydroxy-3-(5-methoxy-[1,1':4',1''-terphenyl]-2-yl)acrylamide
  • (2E)-3-(2-{[1,1'-biphenyl]-4-yl}-4-methoxyphenyl)-N-hydroxyprop-2-enamide
  • 1417997-93-3
  • 417997-93-3
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