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Flumetason

Flumethasone Struktur
2135-17-3
CAS-Nr.
2135-17-3
Bezeichnung:
Flumetason
Englisch Name:
Flumethasone
Synonyma:
fluvet;FLUCORT;rs-2177;ANIPRIME;anaprime;methagon;NSC-54702;CORTEXILAR;ha-methyl-;umethasone
CBNumber:
CB2324823
Summenformel:
C22H28F2O5
Molgewicht:
410.45
MOL-Datei:
2135-17-3.mol

Flumetason Eigenschaften

Schmelzpunkt:
237-240°C
Siedepunkt:
569.8±50.0 °C(Predicted)
Dichte
1.1621 (estimate)
storage temp. 
2-8°C
L?slichkeit
acetic acid: soluble10mg/mL
Aggregatzustand
solid
pka
11.98±0.70(Predicted)
Farbe
white
Optische Aktivit?t
[α]25/D 67.0 to 71.0°, c = 1 in dioxane
Wasserl?slichkeit
1mg/L(20 ºC)
Merck 
14,4138
InChIKey
WXURHACBFYSXBI-GQKYHHCASA-N
CAS Datenbank
2135-17-3(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 40
S-S?tze: 22-36
WGK Germany  3
RTECS-Nr. TU3832000
HS Code  29144000
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H351 Kann vermutlich Krebs verursachen. Karzinogenit?t Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
Sicherheit
P281 Vorgeschriebene pers?nliche Schutzausrüstung verwenden.

Flumetason Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R40:Verdacht auf krebserzeugende Wirkung.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Beschreibung

Flumethasone is an agonist of glucocorticoid and mineralocorticoid receptors with EC50 values of 0.26 and 0.494 nM, respectively, in CV-1 cells expressing human receptors. In vitro, it inhibits the growth of UM-UC-3, TCC-SUP, and 5637 urothelial carcinoma cell lines at a concentration of 100 nM. Flumethasone (5 mg per animal) decreases tumor necrosis factor (TNF) production ex vivo in blood cells collected by bronchoalveolar lavage (BAL) from calves with experimentally-induced local lung inflammation. It also inhibits phytohemagglutinin-induced delayed hypersensitivity in calf skin. In vivo, flumethasone (5 μM) impairs cell cycle re-entry of cardiac cells seven days post cryo-injury to the heart and impairs cardiac regeneration in zebrafish.

Chemische Eigenschaften

White Solid

Flumetason Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Flumetason Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 423)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649
sarah@tnjone.com China 1143 58
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106
sales@frappschem.com China 880 50
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21639 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682
bruce@xrdchem.cn CHINA 566 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29886 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8816 58
Cangzhou Wanyou New Material Technology Co.,Ltd
18631714998
sales@czwytech.com CHINA 904 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845
sales@amoychem.com China 6383 58

2135-17-3(Flumetason)Verwandte Suche:


  • 6-alpha,9-alpha-difluoro-11-beta,17-alpha,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
  • 6α,9α-Difluoro-16α-methylprednisolone
  • 6α-Fluorodexamethasone
  • 6a-Fluoro-dexamethasone, Aniprime, Cortexilar, Flucort
  • Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6.alpha.,11.beta.,16.alpha.)-
  • 6α,9α-difluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione
  • FlumethasoneBase98.5%
  • (6-alpha,11-beta,16-alpha)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • Flumethazone
  • flumetasone
  • CORTEXILAR
  • FLUCORT
  • FLUMETHASONE
  • ANIPRIME
  • 6a,9a-difluoro-16a-methyl-11b,17a,21-trihydroxy-1,4-pregnadiene-3,20-dione
  • 6a,9a-difluoro-16a-methylprednisolone
  • 6A-FLUORO-DEXAMETHASONE
  • 6ALPHA,9ALPHA-DIFLUORO-16ALPHA-METHYL-11BETA,17ALPHA,21-TRIHYDROXY-1,4-PREGNADIENE-3,20-DIONE
  • 6ALPHA,9ALPHA-DIFLUORO-16ALPHA-METHYLPREDNISOLONE
  • 6ALPHA-FLUORODEXAMETHASONE
  • 1,4-PREGNADIEN-6-ALPHA, 9-ALPHA-DIFLUORO-16-ALPHA-METHYL-11-BETA, 17,21-TRIOL-3,20-DIONE
  • anaprime
  • flucorticin
  • flumethason
  • fluvet
  • ha-methyl-
  • methagon
  • rs-2177
  • 6α,9α-Difluoro-16α-methylprednisolone, 6α-Fluorodexamethasone, 6α,9α-Difluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione
  • Cortexillar
  • NSC-54702
  • Flumethasone,6α,9α-Difluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, 6α,9α-Difluoro-16α-methylprednisolone, 6α-Fluorodexamethasone
  • FluMetahsone
  • FULUMETHASONE
  • Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6α,11β,16α)-
  • Flumethasone Solution, 100ppm
  • Flumetasone (double dexamethasone)
  • Flumethasone, >=99%
  • 3-(4-methylpent-3-enyl)-2,5-dihydrothiophene 1,1-dioxide
  • lumethasone
  • Flumetazone
  • Flumethasone sky
  • flumetasone cas: 2135-17-3
  • 6alpha,9-Difluoro-11beta,17,21-trih
  • umethasone
  • Pregna-1,4-diene-3,20-dione,6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6a,11b,16a)-
  • Flumethasone USP/EP/BP
  • Flumethasone 2135-17-3
  • Flumetasone pivalate EP Impurity A
  • Flumethasone (Flumetasone)
  • 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione (Flumetasone)
  • (6S,8S,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • 1, 4-PREGNADIEN-6α, 9α-DIFLUORO-16α-METHYL-11β, 17, 21-TRIOL-3, 20-DIONE
  • (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
  • C13718500 Flumethasone
  • Flumethasone in Acetonitrile
  • 2135-17-3
  • C22H28F2O5
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