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4-Hydroxy-4'-isopropoxydiphenylsulfone

4-Hydroxy-4'-isopropoxydiphenylsulfone Struktur
95235-30-6
CAS-Nr.
95235-30-6
Englisch Name:
4-Hydroxy-4'-isopropoxydiphenylsulfone
Synonyma:
BPS-monoP;UBA7;UBE2;D-8.;UBE1L;UBA1B;D8(HPS);MGC12713;WinCon-8;F-108(D-8)
CBNumber:
CB2324449
Summenformel:
C15H16O4S
Molgewicht:
292.35
MOL-Datei:
95235-30-6.mol

4-Hydroxy-4'-isopropoxydiphenylsulfone Eigenschaften

Schmelzpunkt:
129 °C
Siedepunkt:
478.8±30.0 °C(Predicted)
Dichte
1.251±0.06 g/cm3(Predicted)
Dampfdruck
0Pa at 27℃
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
0.891 in mg/100g standard fat at 20 ℃
Aggregatzustand
powder to crystal
pka
7.24±0.15(Predicted)
Farbe
White to Almost white
Wasserl?slichkeit
19.7mg/L at 25℃
InChI
InChI=1S/C15H16O4S/c1-11(2)19-13-5-9-15(10-6-13)20(17,18)14-7-3-12(16)4-8-14/h3-11,16H,1-2H3
InChIKey
ZTILAOCGFRDHBH-UHFFFAOYSA-N
SMILES
C1(O)=CC=C(S(C2=CC=C(OC(C)C)C=C2)(=O)=O)C=C1
LogP
3.36 at 25℃
CAS Datenbank
95235-30-6(CAS DataBase Reference)
EPA chemische Informationen
Phenol, 4-[[4-(1-methylethoxy)phenyl]sulfonyl]- (95235-30-6)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher N
R-S?tze: 51/53
S-S?tze: 61
HS Code  2930.90.2900
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H411 Giftig für Wasserorganismen, mit langfristiger Wirkung. Langfristig (chronisch) gew?ssergef?hrdend Kategorie 2
Sicherheit

4-Hydroxy-4'-isopropoxydiphenylsulfone Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R51/53:Giftig für Wasserorganismen, kann in Gew?ssern l?ngerfristig sch?dliche Wirkungen haben.

S-S?tze Betriebsanweisung:

S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.

Verwenden

For color developing dyes, various types of dye such as fluoran, phthalide, lactam, triphenylmethane, spiropyran and other types of leuco dyes can be used, but usable dyes are not limited to these only. Besides, these color developing dyes can be mixed in different combinations.

Sicherheit(Safety)

4-Hydroxy-4′-isopropoxydiphenylsulfone (BPSIP), a novel alternative to BPA, is frequently detected in breast milk and the placental barrier system, suggesting that it may be transmitted from mother to offspring and increase the risk of exposure. In a study of the behavioral and neurobiological effects of early-life exposure to BPSIP (0.02, 0.1, and 0.5 mg/kg body weight/day) in mouse offspring, BPSIP exposure induced ASD-like behaviors in male and female pups, including increased anxiety-related behaviors and decreased spatial memory. A clear pattern of decreased social novelty was observed only in female offspring, accompanied by significant changes in antioxidant levels. In addition, decreased protein levels of complex IV (COX IV) in all tested populations suggest a significant impact on mitochondrial function, which may contribute to abnormal energy metabolism in autism. Changes in synaptic proteins, as evidenced by altered levels of synapsin 1 (SYN1) and postsynaptic density protein 95 (PSD95) in the cerebellum and hippocampus, support the idea of synaptic involvement. These findings suggest that BPSIP may induce sex-specific neurotoxic effects involving oxidative stress, energy production, and synaptic plasticity[1].

Synthese

30.3 g of bis(p-hydroxyphenyl)sulfone, 18.5 g of isopropylbromide, and 22.2 g of potassium carbonate as acid-binding agent were added to 200 ml of dimethylformamide, then stirred for 4 hours at about 120° C. and dimethylformamide was distilled off under reduced pressure. When this was accomplished, chloroform was added to the residue to extract crude 4-hydroxy-4'-isopropoxydiphenylsulfone. Then this crude compound was refined by using a silica gel column chromatography and 15.7 g of 4-hydroxy-4'-isopropoxydiphenylsulfone was obtained in white microfine crystals with a melting point of 129.0°~131.0° C.

4-Hydroxy-4'-isopropoxydiphenylsulfone Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


4-Hydroxy-4'-isopropoxydiphenylsulfone Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 219)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Dalian Richfortune Chemicals Co., Ltd
0411-84820922 8613904096939
sales@richfortunechem.com China 304 57
CD Chemical Group Limited
+8615986615575
info@codchem.com China 20342 58
Wuhan ShuEr Biology Technology Co.,Ltd
+86-15629032529
excellentsuppliers@shuerbio.com China 897 58
Changzhou waston chemical technology Co.,Ltd
+86-051985861892 +8618112881323
info@wastonchem.com China 260 58
Weifang Dayoo Biochemical Co., Ltd.,
+undefined13305362020
sales@dayoochemical.com China 20 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177
peter@yan-xi.com China 5857 58
Hebei Weibang Biotechnology Co., Ltd
+8617732866630
bess@weibangbio.com China 18151 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 +86-16264648883
niki@zlchemi.com China 2691 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 18751 58

95235-30-6()Verwandte Suche:


  • WinCon-8 (4-Hydroxy-4'-Isopropoxydiphenylsulfon
  • 4-Hydroxy-4'-isoprop
  • 4-hydroxy-4-Isopropoxydiphenylsulfone (D-8)
  • Anti-UBE1L, C-Terminal antibody produced in rabbit
  • Ubiquitin-activating enzyme 7
  • Ubiquitin-activating enzyme E1 homolog
  • ANTI-UBA7(N-TERMINAL) antibody produced in rabbit
  • UBA7
  • UBE1L
  • UBE2
  • Ubiquitin-like modifier-activating enzyme 7
  • MGC12713
  • Monoclonal Anti-UBA7 antibody produced in mouse
  • UBA1B
  • 4-HYDROXY-4'-ISOPROPOXYDIPHENYLSULFONE
  • 4-HYDROXY-4-ISOPROPOXYDIPHENYLSULFONE
  • 4-ISOPROPOXYPHENYL-4'-HYDROXYPHENYL SULFONE
  • 4-ISOPROPYLOXYPHENYL-4'-HYDROXYPHENYLSULFONE
  • D-8 DEVELOPER
  • D8(HPS)
  • 4-hydroxy-4'-isopropoxydiphenylsulphone
  • 4-hydroxy-4'-isopropoxydiphenylsulfone(D-8) developer
  • D8(HPS)4-ISOPROPYLOXYPHENYL-4'-HYDROXYPHENYLSULFONE
  • 4-Hydroxy-4'-IsopropoxydiphenylsulfonedeveloperD-8
  • D-8.
  • 4-HYDROXY-4'' -CISOPROPOXYDIPHENYLSULFONE
  • 4-(4-Isopropoxyphenylsulfonyl)phenol
  • Phenol,4-[[4-(1-methylethoxy)phenyl]sulfonyl]-
  • 4-[[4-(1-Methylethoxy)phenyl]sulfonyl]phenol
  • 4-Hydroxyphenyl 4-isopropoxyphenyl sulfone
  • 4-(4-Isopropoxyp
  • 4-HYDROXY-4''-ISOPROPOXYDIPHENYLSULFONE(D-8) DEVELOPER 99%
  • 4-Hydroxy-4'-isopropoxydiphenylsulfone 95235-30-6
  • WinCon-8
  • DL-Homocystine-3,3,3&rsquo
  • 4,4,4&rsquo
  • F-108(D-8)
  • 4-Hydroxy-4-isopropoxydiphenylsulfone 99%
  • 4-(4-propan-2-yloxyphenyl)sulfonylphenol
  • UBE1L (Ubiquitin-like modifier-activating enzyme 7 
  • BPS-monoP
  • D8/4-hydroxy-4 '- isopropoxydiphenylsulfone/thermosensitive dye D-8
  • 4-Hydroxy-4'-isopropoxydiphenylsulfone
  • 4-Hydroxy-4'-isopropoxydiphenylsulfone(D8)
  • Thermal paper developer D8
  • 4-Isopropyloxyphenyl-4'-Hydroxyphenylsulfone
  • 4-[(4-Isopropoxyphenyl)sulfonyl]phenol (D8 )
  • 95235-30-6
  • 85235-80-6
  • 85235-80-6
  • 95235-30-3
  • C15H16SO4
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