成人免费xx,国产又黄又湿又刺激不卡网站,成人性视频app菠萝网站,色天天天天

2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline

2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline Struktur
1609394-10-6
CAS-Nr.
1609394-10-6
Englisch Name:
2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline
Synonyma:
2-Methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)benzenamine;Benzenamine, 2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)-;EOS-61512;Deucravacitinib Impurity 8;BMS-986165 Related Compound 3;2-Methoxy-3-(1-methyl-1,2,4-triazol-3-YL)aniline;2-methoxybenzyl carbamimidothioate hydrochloride;2-Methoxy-3-(1-methy-1H-1 ,2,4-triazol-3-yl)aniline;2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline;2-methoxy-3- (1-methyl-1H-1,2,4-triazole-3-yl) aniline
CBNumber:
CB23122644
Summenformel:
C10H12N4O
Molgewicht:
204.23
MOL-Datei:
1609394-10-6.mol

2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline Eigenschaften

Siedepunkt:
437.6±55.0 °C(Predicted)
Dichte
1.29±0.1 g/cm3(Predicted)
L?slichkeit
DMSO (Slightly)
pka
3.45±0.10(Predicted)
Aggregatzustand
Solid
Farbe
Pale Orange to Brown
InChI
InChI=1S/C10H12N4O/c1-14-6-12-10(13-14)7-4-3-5-8(11)9(7)15-2/h3-6H,11H2,1-2H3
InChIKey
FIAZRZSVFOMYSD-UHFFFAOYSA-N
SMILES
C1(N)=CC=CC(C2N=CN(C)N=2)=C1OC

Sicherheit

2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

white solid

Verwenden

2-Methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline is used in the preparation of pyridazines which is a heterodimeric cytokines modulators for treatment of diseases.

Synthese

To a high pressure reactor flushed with nitrogen were charged methanol (8.0 kg/kg) and Compound 6 (1.0 kg). With careful exclusion of oxygen, sodium bicarbonate (0.6 kg/kg, 2.0 equiv.) and Pd/C (10% loading, 50 % wet, 0.02 kg/kg)  were added. The reactor was pressurized with hydrogen (41-46 psi), and the reaction mixture was aged at 20 °C for 6 h then heated to 45 °C and aged till reaction reached completion. The reactor was flushed with nitrogen, and the reaction crude was filtered to remove Pd/C. Methanol (5 kg/kg) was used to aid the transfer. The combined filtrates were distilled under vacuum until total volume became approximately 2.5 L/kg. Water (10 kg/kg) was added, and the crude was distilled under vacuum until total volume became approximately 2.5 L/kg. The crude was heated to 70 °C. Brine (25 wt%, 9.0 kg/kg) was added, and the resulting crude was agitated for 6 h at 70 °C. After cooling down to 0 °C, the crude was further aged for 6 h. Product was isolated by filtration. The cake was washed with brine (pre-cooled to 0 °C, 25 wt%, 2.0 kg/kg), and dried under vacuum at 45 °C.  2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline was isolated in 99 AP and 88% yield.
synthesis of 2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline

2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 160)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Unibest Industrial Co.,Ltd.
+86-8657427855777 +86-18758850676
info@unibestcn.com China 227 58
Shanghai Joiny Pharmaceutical Co.,LTD
+8613681955282
gyd@joiny-pharma.com China 311 58
Hangzhou ICH Biofarm Co., Ltd
+86-0571-28186870; +undefined8613073685410
sales@ichemie.com China 1001 58
Jinan Jianfeng Chemical Co., Ltd
0531-88110457; +8615562555968
info@pharmachemm.com China 251 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830
figo.gao@foxmail.com China 8497 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196
sale04@alfachem.cn China 11817 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695
laboratory@coreychem.com China 30238 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19908 58
Labnetwork lnc.
+86-27-50766799 +8618062016861
contact@labnetwork.com China 19987 58

  • 2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline
  • 2-Methoxy-3-(1-methyl-1H-[1,2,4]triazol-3-yl)-phenylamine
  • 2-Methoxy-3-(1-methyl-1,2,4-triazol-3-YL)aniline
  • BMS-986165 Related Compound 3
  • EOS-61512
  • Benzenamine, 2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)-
  • 2-Methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)benzenamine
  • 2-methoxybenzyl carbamimidothioate hydrochloride
  • 2-Methoxy-3-(1-methy-1H-1 ,2,4-triazol-3-yl)aniline
  • 2-methoxy-3- (1-methyl-1H-1,2,4-triazole-3-yl) aniline
  • Deucravacitinib Impurity 8
  • 1609394-10-6
Copyright 2019 ? ChemicalBook. All rights reserved