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4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-Butenoic acid

4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-Butenoic acid Struktur
139262-76-3
CAS-Nr.
139262-76-3
Englisch Name:
4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-Butenoic acid
Synonyma:
H2L5186303;H2L5186303 >=98% (HPLC);4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-Butenoic acid;(Z,Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-butenoic acid;(2Z,2′Z)-4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-butenoic acid;2-Butenoic acid, 4,4'-[1,3-phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-, (Z,Z)- (9CI);(2Z)-3-{[4-(3-{4-[(2Z)-3-carboxyprop-2-enamido]phenoxy}phenoxy)phenyl]carbamoyl}prop-2-enoic acid;(2Z,2'Z)-4,4'-(((1,3-Phenylenebis(oxy))bis(4,1-phenylene))bis(azanediyl))bis(4-oxobut-2-enoic acid)
CBNumber:
CB22750709
Summenformel:
C26H20N2O8
Molgewicht:
488.45
MOL-Datei:
139262-76-3.mol

4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-Butenoic acid Eigenschaften

storage temp. 
2-8°C
L?slichkeit
DMSO: soluble25mg/mL, clear
Aggregatzustand
powder
Farbe
white to beige
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.

Sicherheit

WGK Germany  3

4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-Butenoic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

H2L5186303 is an antidepressant acting on the LPA1 (lysophosphatidic acid receptor 1) and induce insulin-like growth factor-I receptor transactivation as well as causing enhanced cell proliferation.

Biochem/physiol Actions

H2L5186303 is specific antagonist of the lysophosphatidic acid receptor LPA2 (Ki = 7.2 nM). The compound H2L5186303 displays 40- to 1800-fold selectivity over other LPA receptors.

4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-Butenoic acid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-Butenoic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • (2Z,2′Z)-4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-butenoic acid
  • 4,4′-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-Butenoic acid
  • H2L5186303
  • (Z,Z)-4,4'-[1,3-Phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-2-butenoic acid
  • 2-Butenoic acid, 4,4'-[1,3-phenylenebis(oxy-4,1-phenyleneimino)]bis[4-oxo-, (Z,Z)- (9CI)
  • H2L5186303 >=98% (HPLC)
  • (2Z,2'Z)-4,4'-(((1,3-Phenylenebis(oxy))bis(4,1-phenylene))bis(azanediyl))bis(4-oxobut-2-enoic acid)
  • (2Z)-3-{[4-(3-{4-[(2Z)-3-carboxyprop-2-enamido]phenoxy}phenoxy)phenyl]carbamoyl}prop-2-enoic acid
  • 139262-76-3
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