ARC Polyclonal Antibody Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain-
containing cell death regulators included RAIDD, Apaf-
1, caspase-
9, and caspase-
2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-
2 and -
8 and inhibits enzymatic activity of caspase-
8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-
1 and DR3. The mRNA for ARC is expressed primarily in skeletal muscle and cardiac tissues.
ARC Polyclonal Antibody Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
