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N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide Struktur
1190378-57-4
CAS-Nr.
1190378-57-4
Englisch Name:
N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide
Synonyma:
CS-2840;MRT68921;MRT67307;MRT67307 HCl;MRT67307 (free base);MRT67307 hydrochloride;MRT67307 HCl(free-base);IKKε/TBK1 Inhibitor II, MRT67307 - CAS 1190378-57-4 - Calbiochem;N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide;Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-
CBNumber:
CB22547040
Summenformel:
C26H36N6O2
Molgewicht:
464.6
MOL-Datei:
1190378-57-4.mol

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide Eigenschaften

Dichte
1.270
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
L?slichkeit
H2O: soluble15mg/mL, clear
Aggregatzustand
powder
pka
15.94±0.20(Predicted)
Farbe
white to light brown
InChIKey
UKBGBACORPRCGG-UHFFFAOYSA-N

Sicherheit

WGK Germany  3

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

MRT67307 hydrochloride has been used to study its effect on LPS (lipopolysaccharide) -induced lysosome tubulation.

Biochem/physiol Actions

MRT67307 is an amino-pyrimidine derivative and has an IC50 value of 19. It is known to induce TLR (toll like receptor) mediated anti inflammatory cytokine generation. Also, MRT67307 prevents the secretion of cytokines associated with proinflammation.

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 89)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32820 60
Shandong chuangyingchemical Co., Ltd. 		18853181302
sale@chuangyingchem.com CHINA 5906 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49374 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32002 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38460 58
GIHI CHEMICALS CO.,LIMITED 		+8618058761490
 info@gihichemicals.com China 49979 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652
 info@fdachem.com China 20288 58
  • MRT67307
  • MRT67307 hydrochloride
  • N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-cyclobutanecarboxamide hydrochloride
  • MRT68921
  • N-[3-[[5-Cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]cyclobutanecarboxamide
  • MRT67307 (free base)
  • IKKε/TBK1 Inhibitor II, MRT67307 - CAS 1190378-57-4 - Calbiochem
  • MRT67307 HCl
  • CS-2840
  • Cyclobutanecarboxamide, N-[3-[[5-cyclopropyl-2-[[3-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]propyl]-
  • MRT67307 HCl(free-base)
  • 1190378-57-4
  • C26H36N6O2xHCl
  • NF-kB
  • API
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