2-Amino-5-bromo-3-(hydroxymethyl)pyridine
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- CAS-Nr.
- 335031-01-1
- Englisch Name:
- 2-Amino-5-bromo-3-(hydroxymethyl)pyridine
- Synonyma:
- 2-broMo-4-ethoxypyriMidine;2-Amino-5-Bromo-3-(Hydroxymeth;2-Amino-5-bromopyridine-3-methanol;2-Amino-5-bromo-3-pyridinemethanol;3-Pyridinemethanol, 2-amino-5-bromo-;(2-AMINO-5-BROMO-3-PYRIDINYL)METHANOL;2-AMino-3-hydroxyMethyl-5-broMopyridine;(2-AMINO-5-BROMO-PYRIDIN-3-YL)-METHANOL;2-AMino-5-broMo-3-pyridineMethanol, 98+%;2-Amino-5-bromo-3-(hydroxymethyl)pyridine
- CBNumber:
- CB2248055
- Summenformel:
- C6H7BrN2O
- Molgewicht:
- 203.04
- MOL-Datei:
- 335031-01-1.mol
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2-Amino-5-bromo-3-(hydroxymethyl)pyridine Eigenschaften
- Schmelzpunkt:
- 137-140°C
- Siedepunkt:
- 343.5±37.0 °C(Predicted)
- Dichte
- 1.766±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- L?slichkeit
- Acetone, Ethyl Acetate, Methanol
- pka
- 13.16±0.10(Predicted)
- Aggregatzustand
- Solid
- Farbe
- Off-white to yellow
- CAS Datenbank
- 335031-01-1(CAS DataBase Reference)
2-Amino-5-bromo-3-(hydroxymethyl)pyridine Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
2-Amino-5-bromo-3-(hydroxymethyl)pyridine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthese
2-Amino-5-bromo-3-(hydroxymethyl)pyridineBromine (8.4 mL, 189.4 mmol) was added dropwise over 1 hour to a solution of 2- amino-3-(hydroxymethyl)pyridine (19.6 g, 157.8 mmol) in acetic acid (350 mL) at room temperature. The reaction mixture was then stirred overnight. After concentration to dryness, the residue was partitioned between a saturated solution of potassium carbonate (300 mL) and ethyl acetate (200 ml_). The aqueous layer was separated and extracted with ethyl acetate (2 x 200 ml_). The combined organic phases were washed with a saturated solution of sodium chloride (200 ml_), dried over sodium sulfate, filtered and concentrated to dryness. After trituration of the residue in pentane, the title product was obtained as a yellow solid (27.0 g, 84%).
2-Amino-5-bromo-3-(hydroxymethyl)pyridine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
2-Amino-5-bromo-3-(hydroxymethyl)pyridine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 184)Lieferanten
335031-01-1()Verwandte Suche:
- (2-AMINO-5-BROMO-3-PYRIDINYL)METHANOL
- (2-AMINO-5-BROMO-PYRIDIN-3-YL)-METHANOL
- 2-Amino-5-bromopyridine-3-methanol
- 2-Amino-5-bromo-3-(hydroxymethyl)pyridine
- 2-Amino-5-Bromo-3-(Hydroxymeth
- 2-Amino-5-bromo-3-pyridinemethanol
- 2-AMino-3-hydroxyMethyl-5-broMopyridine
- (2-aMino-5-broMopyridin-3-yl)Methanol(2-AMINO-5-BROMO-3-PYRIDINYL)METHANOL
- 2-AMino-5-broMo-3-pyridineMethanol, 98+%
- 3-Pyridinemethanol, 2-amino-5-bromo-
- 2-Amino-5-bromo-3-(hydroxymethyl)pyridine ISO 9001：2015 REACH
- 2-broMo-4-ethoxypyriMidine
- 335031-01-1
- C6H7N2OBr
- Heterocycle-Pyridine series
- Aromatics
- Heterocycles
- Hydroxymethyl's
- Pyridines
- Pyridine
- Heterocyclic Compounds
- pharmacetical
- Pyridine series
