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TYRPHOSTIN A9

TYRPHOSTIN A9 Struktur
10537-47-0
CAS-Nr.
10537-47-0
Englisch Name:
TYRPHOSTIN A9
Synonyma:
AG 17;CS-743;SF 6847;gcp5126;s-15126;RG 50872;ent27910;MALONABEN;MALONOBEN;Malonobene
CBNumber:
CB2245711
Summenformel:
C18H22N2O
Molgewicht:
282.38
MOL-Datei:
10537-47-0.mol

TYRPHOSTIN A9 Eigenschaften

Schmelzpunkt:
141-143℃ (ethanol )
Siedepunkt:
424.99°C (rough estimate)
Dichte
1.0741 (rough estimate)
Brechungsindex
1.5700 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
L?slichkeit
ethanol: 20 mg/mL
Aggregatzustand
solid
pka
7.55±0.40(Predicted)
Farbe
yellow
Stabilit?t:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
CAS Datenbank
10537-47-0(CAS DataBase Reference)
EPA chemische Informationen
Malonoben (10537-47-0)

Sicherheit

Kennzeichnung gef?hrlicher T
R-S?tze: 23/24/25
S-S?tze: 36/37/39-45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS-Nr. OO3737000
HS Code  2926.90.5050
HazardClass  6.1

TYRPHOSTIN A9 Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R23/24/25:Giftig beim Einatmen, Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).

Verwenden

Tyrphostin A9 can be used for inhibiting tyrosine kinase functions in C2C12 cells. It has also been used to disrupt membrane potential in mammalian cells.

Allgemeine Beschreibung

A selective, cell-permeable, reversible, and substrate competitive inhibitor of the platelet-derived growth factor receptor tyrosine kinase (IC50 = 500 nM). Anti-proliferative agent. Uncoupler of oxidative phosphorylation. Induces apoptosis in vitro and cell growth arrest in NHL cell lines.

Biologische Aktivit?t

Potent uncoupler of oxidative phosphorylation.

TYRPHOSTIN A9 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


TYRPHOSTIN A9 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 134)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32951 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29884 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051
joe@yuhengpharm.com CHINA 21142 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32079 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226
sales@hzclap.com CHINA 6312 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22883 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
ShenZhen Trendseen Biological Technology Co.,Ltd.
13417589054
trendseenbio@gmail.com China 11681 58

10537-47-0()Verwandte Suche:


  • ALPHA-CYANO-(3,5-DI-T-BUTYL-4-HYDROXY)CINNAMONITRILE
  • TYRPHOSTIN A9 \ SELECTIVE PDGF TYROSINE
  • TYRPHOSTIN A9 99+%
  • Malonobene
  • 2-(3,5-di-tert-butyl-4-hydroxybenzylidene)Malononitrile
  • Tyrphostin 9 (SF 6847)
  • Propanedinitrile, 2-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-
  • [[3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXYPHENYL]METHYLENE]-PROPANEDINITRILE
  • 3,5-DI-T-BUTYL-4-HYDROXY-BENZYLIDENEMALONONITRILE
  • 3,5-DI-TERT-BUTYL-4-HYDROXYBENZYLIDENEMALONONITRILE
  • AG 17
  • 2-[(3,5-DITERT-BUTYL-4-HYDROXYPHENYL)METHYLIDENE]PROPANEDINITRILE
  • 2,6-Di-tert-butyl-4-(2,2-dicyanovinyl)phenol
  • 3,5-di-tert-Butyl-4-hydroxybenzylidenemalonitrile
  • Tyrphostin 9/AG9
  • TYRPHOSTIN 9;NSC 242557; RG-50872;AG 17; GCP 5126
  • Tyrphostin 9 (RG-50872, Malonaben, SF 6847)
  • NSC 242557
  • SF 6847
  • RARECHEM AL BX 0198
  • RG 50872
  • ((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-propanedinitril
  • 2-((3,5-bis(1,1-dimethyl)-4-hydroxyphenyl)methylene)propanedinitrile
  • 3,5-di-tert-butyl-4-hydroxybenzylidene-malononitril
  • ent27910
  • gcp5126
  • gulfs-15126
  • s-15126
  • TYRPHOSTIN 9
  • TYRPHOSTIN A9
  • TYRPHOSTIN AG 17
  • TYRPHOSTIN RG 50872
  • CHEMBRDG-BB 5272363
  • MALONABEN
  • MALONOBEN
  • Tyrphostin A9 (AG 17)
  • AG 17 - CAS 10537-47-0 - Calbiochem
  • Tyrphostin 9(AG-17)
  • TYRPHOSTIN 9;MALONOBEN;TYRPHOSTIN AG-17;SF 6847;GCP 5126;RG-50872;NSC 242557
  • CS-743
  • Tyrphostin9, >98%
  • TYRPHOSTIN A9OLECARBOXYLATE
  • Tyrphostin 9 (SF 6847, RG-50872)
  • [4-Hydroxy-3,5-bis(2-methyl-2-propanyl)benzylidene]malononitrile
  • TYRPHOSTIN A9 USP/EP/BP
  • Malonoben Tyrphostin 9
  • C17896100 Tyrphostin A9
  • 10537-47-0
  • Inhibitor of calcium release-activated calcium (CRAC) channels (see Dennis et al)
  • Cell Signaling and Neuroscience
  • BioChemical
  • Cell Biology
  • Kinase/Phosphatase Biology
  • Receptor Tyrosine Kinase Inhibitors
  • Platelet Derived Growth Factor Receptor (PDGFR)
  • Inhibitors
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