Anti-GOK, Anti-Stromal interaction molecule I Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-STIM1 (N-terminal) antibody produced in rabbit has been used in:
- western blotting
- immunoprecipitation
- immunofluorescence
Allgemeine Beschreibung
STIM1 (stromal interaction molecule 1) is a conserved single-pass transmembrane protein, which is expressed ubiquitously in a wide variety of human primary and transformed cell types. STIM1 is modified by phosphorylation and
N-linked glycosylation. STIM1 localized predominantly in the membrane of the endoplasmic reticulum (ER). It contains an N-terminal EF hand motif located in the ER lumen and appears to function as a sensor of ER Ca
2+ levels.
Biochem/physiol Actions
STIM1 (stromal interaction molecule 1) is required for the activation of store-operated Ca2+ influx. Overexpression of STIM1 and Orai1 markedly increases the calcium release-activated calcium (CRAC) current (I-CRAC).
Anti-GOK, Anti-Stromal interaction molecule I Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
