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Triptolide

Triptolide Struktur
38748-32-2
CAS-Nr.
38748-32-2
Englisch Name:
Triptolide
Synonyma:
(3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one;PG490;Triptolide 38748-32-2;Thunder God Vine Extract;8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-,(3bs,4as,5as,6r,6ar;triptolid;riptolide;TRIPTOLIDE;NSC 163062;TRIPTONIDE(P)
CBNumber:
CB2167404
Summenformel:
C20H24O6
Molgewicht:
360.4
MOL-Datei:
38748-32-2.mol

Triptolide Eigenschaften

Schmelzpunkt:
226-227°C
alpha 
D25 -154°
Siedepunkt:
412.43°C (rough estimate)
Dichte
1.1656 (rough estimate)
Brechungsindex
1.4450 (estimate)
storage temp. 
2-8°C
L?slichkeit
DMSO: soluble
Aggregatzustand
solid
pka
14.25±0.60(Predicted)
Farbe
white to off-white
Biologische Quelle
Tripterygium wilfordii
Merck 
14,9747
Stabilit?t:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey
DFBIRQPKNDILPW-CIVMWXNOSA-N
CAS Datenbank
38748-32-2(CAS DataBase Reference)
EPA chemische Informationen
Trisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)- (38748-32-2)

Sicherheit

S-S?tze: 22-24/25
RIDADR  2811
WGK Germany  3
RTECS-Nr. YK7751000
HazardClass  6.1
PackingGroup  I
HS Code  29321900
Toxizit?t LD50 i.p. in mice: 1.93 mg/kg (Chen)

Triptolide Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

White Crystalline Solid

Verwenden

Triptolide is a diterpenoid triepoxide with immunosuppressant and antitumor properties.

Allgemeine Beschreibung

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biologische Aktivit?t

Inhibits cytokine-induced gene expression via inhibition of NF- κ B transcriptional activity. Induces apoptosis in tumor cells by blocking TNF- α mediated c-IAP2 and c-IAP1 (members of the inhibitor of apoptosis family) induction. Immunosuppressive with anti-inflammatory and antitumor activity.

Triptolide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Triptolide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 447)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083
 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897
 sales@biopurify.com China 3772 58
Xi'an ZB Biotech Co.,Ltd
+8618591943808
 sales01@xazbbio.com China 815 58
Hebei baicao biology science and technology co., ltd
+86-19131911055 +8617824879454
 zhang@hbbocao.com China 1029 58
Hebei Kingfiner Technology Development Co.Ltd 		+86-15532196582 +86-15373005021
 lisa@kingfinertech.com China 3007 58
Shaanxi Haibo Biotechnology Co., Ltd 		+undefined18602966907
 qinhe02@xaltbio.com China 997 58
Anhui Ruihan Technology Co., Ltd 		+8617756083858
 daisy@anhuiruihan.com China 973 58
Chongqing Zhihe Biopharmaceutical Co., Ltd. 		+86-18580541567; +8618580541567
 sales@zhswyy.com China 290 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806
 sales@capot.com China 29792 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21632 55

38748-32-2()Verwandte Suche:

  • TRIPTOLIDE
  • TRIPTOLIDE, TRIPTERYGIUM WILFORDII
  • ,7as,7bs,8as,8bs)-
  • triptolid
  • Triptolide, >=98%
  • TriptolidefromTripterygium wilfordii≥ 98% (HPLC)
  • Triptolide(TPL)
  • TRIPTOLIDE TLC
  • TRIPTOLIDE95%
  • TRIPTOLIDE(P)
  • TRIPTONIDE(P)
  • NSC 163062
  • TRIPTOLIDE(RG)(PLEASE CALL)
  • Tripterygium wilfordii Hook.f.
  • Triptolide(PG490,Triptolid)
  • Triptolide(PG490)
  • (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-
  • Triptolide-d3 (Major, Contains d0)
  • TripterygiuM wilfordii extractive
  • Trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-
  • Triptolide, froM TripterygiuM
  • Triptolide, 98%, from Tripterygium
  • professional supplier Triptolide 38748-32-2
  • Triptolide, Tripterygium wilfordii - CAS 38748-32-2 - Calbiochem
  • Triptolide Triptolide
  • (5bS,6aS,7aS,8R,8aR,9aS,9bS,10aS,10bS)-8-Hydroxy-8a-isopropyl-10b-methyl-1,5,5b,6,6a,8,8a,9a,9b,10b-decahydrotris(oxireno)[2',3':4b,5
  • 2''',3''':8a,9]phenanthro[1,2-c]furan-3(2H)-one
  • riptolide
  • AZD6244 sulfate salt
  • Triptolide ex. Tripterigium Wilfordii for cell culture, 98%
  • PG490
  • 8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-,(3bs,4as,5as,6r,6ar
  • (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one
  • Thunder God Vine Extract
  • Triptolide 38748-32-2
  • 1H-Pyrrole-2,5-dione,4-methyl-
  • Triptolide (ZCI)
  • Triptolide-RM
  • Triptolide from Tripterygium wilfordii, Anti-inflammatory agent
  • Triptolide, 10 mM in DMSO
  • 38748-32-2
  • 8748-32-2
  • Immune System Regulation
  • Immunomodulators and Antibiotics
  • Immune Cell Signaling and Blood
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
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