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illudin M

illudin M Struktur
1146-04-9
CAS-Nr.
1146-04-9
Englisch Name:
illudin M
Synonyma:
illudin M;(3S)-2,3-Dihydro-3α,6β-dihydroxy-2,2,4,6-tetramethylspiro[5H-indene-5,1'-cyclopropan]-7(6H)-one;(3'S,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one;(3'S,6'R)-3',6'-dihydroxy-2',2',4',6'-tetramethyl-2',3',6',7'-tetrahydrospiro[cyclopropane-1,5'-inden]-7'-one;Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethyl-, (3'S,6'R)-
CBNumber:
CB21385676
Summenformel:
C15H20O3
Molgewicht:
248.32
MOL-Datei:
1146-04-9.mol

illudin M Eigenschaften

Schmelzpunkt:
120-122.5° (Matsumoto); mp 128-130° (McMorris)
Siedepunkt:
452.4±45.0 °C(Predicted)
Dichte
1.24±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
Aggregatzustand
A solid
pka
12.57±0.70(Predicted)
Farbe
Off-white to light yellow

Sicherheit

illudin M Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Illudin M is a cytotoxic sesquiterpene from the fungus O. illudens that alkylates DNA. It is cytotoxic to HL-60 human leukemia cells at 6-100 nM. Illudin M was used as a base structure for the development of potential anticancer agents with less toxicity and improved efficacy. It is closely related to illudin S , which has been the focus of additional studies.

Verwenden

Illudin M is a cytotoxic sesquiterpene from Omphalotus illudens and Granulobasidium vellereum. It acts as an alkylating agent that can cause inhibition of cell growth or replication.

illudin M Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

illudin M Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 42)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81148696 +86-15536356810
 1022@dideu.com China 3882 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD. 		+86-021-61551413 +8618813727289
 contact@trustwe.com China 5738 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32024 58
Zhejiang Huida Biotech Co., LTD 		008613515763466 8615669048680
 wendy@huidabiotech.com CHINA 87 58
Shanghai Minbiotech Co., Ltd. 		+8617315815539
 sales@minbiotech.com CHINA 129 58
AFINE CHEMICALS LIMITED 		+86-0571-85134551
sales@afinechem.com China 15361 58
BOC Sciences 		16314854226; +16314854226
 inquiry@bocsci.com United States 19741 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207
 sales@molcore.com China 49734 58
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581
 sales@chemhifuture.com China 3135 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139
 orders@jknbiochem.com China 5221 58

1146-04-9()Verwandte Suche:

  • illudin M
  • (3S)-2,3-Dihydro-3α,6β-dihydroxy-2,2,4,6-tetramethylspiro[5H-indene-5,1'-cyclopropan]-7(6H)-one
  • (3'S,6'R)-2',3'-Dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethylspiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one
  • Spiro[cyclopropane-1,5'-[5H]inden]-7'(6'H)-one, 2',3'-dihydro-3',6'-dihydroxy-2',2',4',6'-tetramethyl-, (3'S,6'R)-
  • (3'S,6'R)-3',6'-dihydroxy-2',2',4',6'-tetramethyl-2',3',6',7'-tetrahydrospiro[cyclopropane-1,5'-inden]-7'-one
  • 1146-04-9
  • ADC
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